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Boots Cystitis Relief (Cranberry Flavour)


Boots Cystitis Relief

(Sodium Citrate)

Cranberry flavour

48 hour complete course

6 sachets

Read all of this carton for full instructions.

What this medicine is for

This medicine contains Sodium Citrate which relieves the symptoms of cystitis in women by making the urine less acidic.

Before you take this medicine Do not take: If you are allergic to any of the ingredients If you have diabetes, heart disease, high blood pressure If you have kidney disease or have had it If you are on a low salt (sodium) diet (each sachet contains 939 mg of sodium) If you have an intolerance to some sugars, unless your doctor tells you to (this medicine contains sucrose) If you are pregnant or breastfeeding How to take this medicine

Check the sachet is not broken before use. If it is, do not take that sachet.

Dissolve the contents of the sachet in a glass of water and drink the solution.

Adult women: Take one sachet dissolved in water, three times a day for 2 days.

Men and children: Not recommended.

You should complete the 2 day course of 6 sachets.

Do not take more than the amount recommended above.

If symptoms do not go away within 2 days talk to your doctor.

If you take too many sachets: Talk to a doctor.

Possible side effects

This medicine is not expected to cause side effects.

If you notice any side effect please tell your pharmacist or doctor.

How to store this medicine

Do not store above 25°C.

Store in a dry place.

Keep all medicines out of the sight and reach of children.

Use by the date on the end flap of the carton.

Active ingredient

Each sachet of granules contains Sodium Citrate Dihydrate 4 g.

Also contains: sucrose, colloidal silicon dioxide, saccharin sodium, cranberry flavour.

PL 12063/0045

Text prepared 9/07

Manufactured for

The Boots Company PLC Nottingham NG2 3AA

by the Marketing Authorisation holder

Wrafton Laboratories Limited Braunton Devon EX33 2DL

If you need more advice ask your pharmacist.

3423aeMC


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Urinary Incontinence Medications


Definition of Urinary Incontinence:

Incontinence is the inability to control the passage of urine. This can range from an occasional leakage of urine, to a complete inability to hold any urine.

The three main types of urinary incontinence are:

Stress incontinence -- occurs during certain activities like coughing, sneezing, laughing, or exercise.

Stress incontinence is a bladder storage problem in which the strength of the muscles (urethral sphincter) that help control urination is reduced. The sphincter is not able to prevent urine flow when there is increased pressure from the abdomen.

Stress incontinence may occur as a result of weakened pelvic muscles that support the bladder and urethra or because of a malfunction of the urethral sphincter.

Treatment for stress incontinence may include behavioral changes, medication, pelvic floor muscle training or surgery.

Urge incontinence -- involves a strong, sudden need to urinate followed by instant bladder contraction and involuntary loss of urine. You don't have enough time between when you recognize the need to urinate and when you actually do urinate.

In most cases of urge incontinence, no specific cause can be identified.Although urge incontinence may occur in anyone at any age, it is more common in women and the elderly.

Treatment for urge incontinence may include medication, retraining, and surgery.

Mixed incontinence -- contains components of both stress and urge incontinence.

Drugs associated with Urinary Incontinence

The following drugs and medications are in some way related to, or used in the treatment of Urinary Incontinence. This service should be used as a supplement to, and NOT a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

See sub-topics

Topics under Urinary IncontinenceOveractive Bladder (18 drugs) Learn more about Urinary Incontinence

Medical Encyclopedia:

Urinary incontinence

Harvard Health Guide:

Symptoms and treatment for Urinary Incontinence
Drug List:/tags/a-spaz/
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/tags/nulev-orally-disintegrating-tablets/
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/tags/symax-fastabs-orally-disintegrating-tablets/
/tags/symax-sr-extended-release-tablets/
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Herbal products


A drug may be classified by the chemical type of the active ingredient or by the way it is used to treat a particular condition. Each drug can be classified into one or more drug classes.

Herbal products are medicines derived from plants. They are used as supplements to improve health and well being, and may be used for other therapeutic purposes. Herbal products are available as tablets, capsules, powders, extracts, teas and so on.

Herbal medicines are thought to be safe as it is natural, but in fact it can cause serious adverse effects and interaction with other drugs and supplements.

See also

Medical conditions associated with herbal products:

Acne ADHD Allergies Anemia Anorexia Anxiety Anxiety and Stress Aphthous Ulcer Asthma Atopic Dermatitis Bacterial Infection Bacterial Skin Infection Benign Prostatic Hyperplasia Bronchitis Burns, External Cancer Chronic Fatigue Syndrome Cold Sores Cold Symptoms Condylomata Acuminata Constipation Constipation, Chronic Coronary Artery Disease Cough Depression Dermatitis Diabetes, Type 1 Diabetes, Type 2 Diabetic Nerve Damage Diarrhea Diarrhea, Acute Diarrhea, Chronic Dry Skin Eczema Enuresis Epicondylitis, Tennis Elbow Epilepsy Erectile Dysfunction Eye Dryness/Redness Eye Redness/Itching Fever Fibromyalgia Gallbladder Disease Gas GERD Gingivitis Gout Headache Heart Disease Hemorrhoids Herbal Supplementation High Blood Pressure High Cholesterol Hot Flashes Human Papilloma Virus Indigestion Infectious Gastroenteritis Inflammatory Conditions Influenza Insomnia Labor Induction Labor Pain Liver Cirrhosis Menopausal Disorders Menstrual Disorders Migraine Migraine Prevention Mild Cognitive Impairment Motion Sickness Muscle Pain Muscle Spasm Nasal Congestion Nausea/Vomiting Neuralgia Night Terrors Nocturnal Leg Cramps Nonalcoholic Fatty Liver Disease Obesity Oral and Dental Conditions Osteoarthritis Otitis Externa Overactive Bladder Peripheral Neuropathy Photoaging of the Skin Postmenopausal Symptoms Premenstrual Dysphoric Disorder Prostate Cancer Psoriasis Rheumatoid Arthritis Rhinorrhea Sciatica Sedation Sinus Symptoms Sinusitis Sjogren's Syndrome Skin and Structure Infection Skin Infection Skin Rash Smallpox Prophylaxis Stomach Ulcer Strep Throat Sunburn Systemic Lupus Erythematosus Tonsillitis/Pharyngitis Upper Respiratory Tract Infection Urinary Incontinence Urinary Tract Infection Urticaria Varicose Veins Vomiting Weight Loss Drug List: Azo-Cranberry Evening-Primrose-Oil 5-Htp Carrington-Oral-Wound-Rinse Ginkgo-Biloba Menopause-Support Oramagic-Rx Primrose-Oil Venastat
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Heparin sodium 100 IU / ml I.V. flush solution (Leo Laboratories Ltd)


1. Name Of The Medicinal Product

HEPARIN SODIUM 100 IU/ml I.V. FLUSH SOLUTION

2. Qualitative And Quantitative Composition

Heparin sodium Ph. Eur. 100 IU/ml

3. Pharmaceutical Form

Solution for Injection.

4. Clinical Particulars 4.1 Therapeutic Indications

To maintain the patency of in-dwelling intravenous lines. It is not recommended for therapeutic use.

4.2 Posology And Method Of Administration

For routine use, 2 ml containing 200 IU of heparin should be administered into the catheter/cannula every 4-8 hours or as required.

4.3 Contraindications

Known hypersensitivity to constituents.

Current or history of heparin induced thrombocytopenia.

Heparin Sodium 100 IU/ml i.v. flush solution contains 10 mg/ml of the preservative benzyl alcohol. This formulation must not be given to premature babies or neonates.

4.4 Special Warnings And Precautions For Use

As there is a risk of antibody-mediated heparin-induced thrombocytopenia, platelet counts should be measured in patients receiving regular and repeated use of heparin flush solutions for longer than 5 days and the treatment should be stopped immediately in those who develop thrombocytopenia.

Heparin induced thrombocytopenia and heparin induced thrombocytopenia with thrombosis can occur up to several weeks after discontinuation of heparin therapy. Patients presenting with thrombocytopenia or thrombosis after discontinuation of heparin should be evaluated for HIT and HITT.

Heparin Sodium 100 IU/ml i.v. flush solution should be used with caution in patients with hypersensitivity to low molecular weight heparin.

Heparin Sodium 100 IU/ml i.v. flush solution contains the preservative benzyl alcohol 10mg/ml. This product should be administered with caution to infants and children up to 3 years old, as there is a risk that benzyl alcohol may cause toxic and allergic reactions (anaphylactoid) in this age group (see also section 4.3 for premature babies or neonates).

Heparin Sodium 100 IU/ml i.v. flush solution contains esters of parahydroxybenzoates as a preservative system. These may cause allergic reactions (possibly delayed), and exceptionally, bronchospasm.

4.5 Interaction With Other Medicinal Products And Other Forms Of Interaction

For incompatibilities with other medicinal products see Section 6.2.

When an indwelling device is used for repeated withdrawal of blood samples for laboratory analyses and the presence of heparin or saline is likely to interfere with or alter the results of the tests, the in situ heparin flush solution should be cleared from the device by aspirating and discarding a volume of solution equivalent to that of the indwelling venipuncture device before the desired blood sample is taken.

4.6 Pregnancy And Lactation

The dose of heparin used would not be expected to constitute a hazard. However, as benzyl alcohol may cross the placenta, the use of Heparin Sodium 100 IU/ml i.v. flush solution containing benzyl alcohol should be avoided during pregnancy.

Heparin does not cross the placental barrier and is not excreted in breast milk.

4.7 Effects On Ability To Drive And Use Machines

Heparin has no or negligible influence on the ability to drive or use machines.

4.8 Undesirable Effects

When used as recommended, the low dose of heparin reaching the blood is unlikely to have any systemic effects. However, heparin may cause thrombocytopenia and hypersensitivity reactions.

Local irritation may occur if inadvertently injected subcutaneously.

4.9 Overdose

An overdose is unlikely to occur. Bleeding is the main sign of overdose with heparin. As heparin is eliminated quickly, a discontinuation of treatment is sufficient in case of minor haemorrhages. In case of severe haemorrhages heparin may be neutralised with protamine sulphate injected slowly intravenously. One mg of protamine sulphate neutralises approximately 100 IU of heparin. Nevertheless, the required protamine sulphate dose varies according to the time of heparin administration and the dose administered.

It is important to avoid overdosage of protamine sulphate because protamine sulphate itself has anticoagulant properties. A single dose of protamine sulphate should never exceed 50 mg. Intravenous injection of protamine sulphate may cause a sudden fall in blood pressure, bradycardia, dyspnoea and transitory flushing, but these may be avoided or diminished by slow and careful administration.

5. Pharmacological Properties 5.1 Pharmacodynamic Properties

Heparin is a naturally occurring anticoagulant which prevents the coagulation of blood in-vivo and in-vitro. It potentiates the inhibition of several activated coagulation factors, including thrombin and factor X.

5.2 Pharmacokinetic Properties

Not applicable

5.3 Preclinical Safety Data

There are no preclinical data of relevance to the prescriber which are additional to that already included in other sections of the Summary Product Characteristics.

6. Pharmaceutical Particulars 6.1 List Of Excipients

Benzyl alcohol,

Methylparahydroxybenzoate,

Propylparahydroxybenzoate,

Sodium citrate,

Sodium chloride,

Water for Injections.

6.2 Incompatibilities

This product is compatible with normal saline. Heparin has been reported to be incompatible in aqueous solution with certain substances, e.g. some antibiotics, hydrocortisone, phenothiazines, narcotic analgesics and antihistamines.

6.3 Shelf Life

3 years.

6.4 Special Precautions For Storage

Do not store above 25?C.

6.5 Nature And Contents Of Container

10 x 2 ml ampoules.

6.6 Special Precautions For Disposal And Other Handling

None

7. Marketing Authorisation Holder

LEO Laboratories Limited

Longwick Road

Princes Risborough

Bucks HP27 9RR

8. Marketing Authorisation Number(S)

PL 0043/0057

9. Date Of First Authorisation/Renewal Of The Authorisation

23 October 1978/16 January 1995

10. Date Of Revision Of The Text

November 2007

LEGAL CATEGORY

POM


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Heparins


A drug may be classified by the chemical type of the active ingredient or by the way it is used to treat a particular condition. Each drug can be classified into one or more drug classes.

Heparin is an injectable anticoagulant that activates antithrombin III, which inhibits thrombin and factor Xa, factors necessary in the final stages of blood clotting cascade.

There are two types of heparins: high molecular weight heparins and low molecular weight heparins.

High molecular weight heparins require daily blood monitoring to check the aPTT. Low molecular weight heparins give a better anticoagulant response and do not need daily blood monitoring.

Heparin is used to treat or prevent clots in conditions where there is a high risk of clot formation and thromboembolism, such as in atrial fibrillation, myocardial infarction, deep vein thrombosis, knee and hip surgery and so on.

See also

Medical conditions associated with heparins:

Acute Coronary Syndrome Angina Anticoagulation During Pregnancy Antiphospholipid Syndrome Deep Vein Thrombosis Deep Vein Thrombosis Prophylaxis after Abdominal Surgery Deep Vein Thrombosis Prophylaxis after Hip Replacement Surgery Deep Vein Thrombosis Prophylaxis after Knee Replacement Surgery Deep Vein Thrombosis Prophylaxis after Orthopedic Surgery Deep Vein Thrombosis, Prophylaxis Heart Attack Patency Maintenance of Indwelling Intravenous Devices Pulmonary Embolism Thrombotic/Thromboembolic Disorder Venous Thromboembolism Drug List: Fragmin Innohep Lovenox Normiflo Heparin-Lock-Flush Heparin-Sodium Orgaran
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atropine, hyoscyamine, methenamine, methylene blue, phenyl salicylate, and benzoic acid


AT-roe-peen SUL-fate, hye-oh-SYE-a-meen SUL-fate, meth-EN-a-meen, METH-i-leen BLOO, FEN-il sal-I-si-late, ben-ZOE-ik AS-id

Commonly used brand name(s)

In the U.S.

Prosed EC Trac Tabs Urised

Available Dosage Forms:

Tablet Tablet, Enteric Coated

Therapeutic Class: Urinary Antispasmodic

Pharmacologic Class: Atropine

Chemical Class: Salicylate, Non-Aspirin

Uses For atropine, hyoscyamine, methenamine, methylene blue, phenyl salicylate, and benzoic acid

Atropine , hyoscyamine , methenamine , methylene blue, phenyl salicylate , and benzoic acid combination medicine is an anticholinergic, anti-infective, and analgesic. It is given by mouth to help relieve the discomfort caused by urinary tract infections; however, it will not cure the infection itself. This combination medicine may also be used for other conditions as determined by your doctor.

atropine, hyoscyamine, methenamine, methylene blue, phenyl salicylate, and benzoic acid is available only with your doctor's prescription.

Before Using atropine, hyoscyamine, methenamine, methylene blue, phenyl salicylate, and benzoic acid

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For atropine, hyoscyamine, methenamine, methylene blue, phenyl salicylate, and benzoic acid, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to atropine, hyoscyamine, methenamine, methylene blue, phenyl salicylate, and benzoic acid or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Unusual excitement, nervousness, restlessness or irritability, and unusual warmth, dryness, and flushing of skin are more likely to occur in children, who are usually more sensitive to the effects of atropine and hyoscyamine (contained in this combination medicine). Also, when atropine and hyoscyamine are given to children during hot weather, a rapid increase in body temperature may occur. In infants and children, especially those with spastic paralysis or brain damage, atropine, hyoscyamine, methenamine, methylene blue, phenyl salicylate, and benzoic acid may be more likely to cause severe side effects.

Geriatric

Confusion or memory loss, constipation, difficult urination, excitement, agitation, drowsiness, or dryness of mouth may be more likely to occur in elderly patients, who are usually more sensitive than younger adults to the effects of atropine and hyoscyamine. Also, this combination medicine may cause eye pain in patients who have untreated glaucoma.

Pregnancy Pregnancy Category Explanation All Trimesters X Studies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities. This drug should not be used in women who are or may become pregnant because the risk clearly outweighs any possible benefit. Breast Feeding Benzoic Acid

Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

Methylene BlueBenzyl BenzoateMethenamineAtropineHyoscyamine

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking atropine, hyoscyamine, methenamine, methylene blue, phenyl salicylate, and benzoic acid, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using atropine, hyoscyamine, methenamine, methylene blue, phenyl salicylate, and benzoic acid with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Ambenonium Amitriptyline Amoxapine Bupropion Citalopram Clomipramine Desipramine Desvenlafaxine Doxepin Duloxetine Escitalopram Fluoxetine Fluvoxamine Imipramine Isocarboxazid Linezolid Maprotiline Mirtazapine Nortriptyline Paroxetine Phenelzine Potassium Protriptyline Selegiline Sertraline Tranylcypromine Trimipramine Venlafaxine Vilazodone

Using atropine, hyoscyamine, methenamine, methylene blue, phenyl salicylate, and benzoic acid with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Buspirone Nefazodone Trazodone

Using atropine, hyoscyamine, methenamine, methylene blue, phenyl salicylate, and benzoic acid with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Arbutamine Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Other Medical Problems

The presence of other medical problems may affect the use of atropine, hyoscyamine, methenamine, methylene blue, phenyl salicylate, and benzoic acid. Make sure you tell your doctor if you have any other medical problems, especially:

Bleeding problems (severe)—This combination medicine may increase heart rate, which would make bleeding problems worse Brain damage (in children)—May increase the central nervous system (CNS) effects of this combination medicine Colitis (severe) or Dryness of mouth (severe or continuing) or Enlarged prostate or Fever or Glaucoma or Heart disease or Hernia (hiatal) or High blood pressure or Intestinal blockage or other intestinal or stomach problems or Lung disease or Myasthenia gravis or Toxemia of pregnancy or Urinary tract blockage or difficult urination—This combination medicine may make these conditions worse Dehydration or Kidney disease or Liver disease—Higher levels of medicine may result and increase the risk of side effects Overactive thyroid—May increase the heart rate Proper Use of atropine, hyoscyamine, methenamine, methylene blue, phenyl salicylate, and benzoic acid

While you are taking this combination medicine, it is important for your urine to be acidic. To do this, your doctor may recommend that you eat more protein and such foods as cranberries (especially cranberry juice with vitamin C added), plums, or prunes. You should avoid foods that make the urine more alkaline, such as most fruits (especially citrus fruits and juices), milk, and other dairy products.

Take atropine, hyoscyamine, methenamine, methylene blue, phenyl salicylate, and benzoic acid only as directed. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects.

Each dose should be taken with a full glass (8 ounces) of water or other liquid (except citrus juices and milk). Drink plenty of water or other liquids every day, unless otherwise directed by your doctor. Drinking enough liquids will help your kidneys work better and lessen your discomfort.

To help clear up your infection completely, keep taking atropine, hyoscyamine, methenamine, methylene blue, phenyl salicylate, and benzoic acid for the full time of treatment even if you begin to feel better after a few days. Do not miss any doses.

In order for atropine, hyoscyamine, methenamine, methylene blue, phenyl salicylate, and benzoic acid to work well, your urine must be acid (pH 5.5 or below). To make sure that your urine is acid:

Before you start taking atropine, hyoscyamine, methenamine, methylene blue, phenyl salicylate, and benzoic acid, check your urine with phenaphthazine paper or another test to see if it is acid. If you have any questions about this, check with your health care professional. You may need to change your diet; however, check with your doctor first if you are on a special diet (for example, for diabetes). To help make your urine more acid you should avoid most fruits (especially citrus fruits and juices), milk and other dairy products, and other foods which make the urine more alkaline. Eating more protein and foods such as cranberries (especially cranberry juice with vitamin C added), plums, or prunes may also help. If your urine is still not acid enough, check with your doctor. Dosing

The dose of atropine, hyoscyamine, methenamine, methylene blue, phenyl salicylate, and benzoic acid will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of atropine, hyoscyamine, methenamine, methylene blue, phenyl salicylate, and benzoic acid. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (tablets): For relief of urinary tract symptoms: Adults and children 12 years of age and older—1 to 2 tablets four times a day. Children 6 to 12 years of age—Dose must be determined by the doctor. Children up to 6 years of age—Use is not recommended. Missed Dose

If you miss a dose of atropine, hyoscyamine, methenamine, methylene blue, phenyl salicylate, and benzoic acid, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using atropine, hyoscyamine, methenamine, methylene blue, phenyl salicylate, and benzoic acid

If your symptoms do not improve within a few days or if they become worse, check with your doctor.

These medicines may make you sweat less, causing your body temperature to increase. Use extra care not to become overheated during exercise or hot weather while you are taking atropine, hyoscyamine, methenamine, methylene blue, phenyl salicylate, and benzoic acid, since overheating may result in heat stroke. Also, hot baths or saunas may make you dizzy or faint while you are taking atropine, hyoscyamine, methenamine, methylene blue, phenyl salicylate, and benzoic acid.

atropine, hyoscyamine, methenamine, methylene blue, phenyl salicylate, and benzoic acid may cause some people to have blurred vision. Make sure you know how you react to atropine, hyoscyamine, methenamine, methylene blue, phenyl salicylate, and benzoic acid before you drive, use machines, or do anything else that could be dangerous if you are not able to see well. If your vision continues to be blurred, check with your doctor.

atropine, hyoscyamine, methenamine, methylene blue, phenyl salicylate, and benzoic acid may cause dryness of the mouth. For temporary relief, use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute. However, if your mouth continues to feel dry for more than 2 weeks, check with your dentist. Continuing dryness of the mouth may increase the chance of dental disease, including tooth decay, gum disease, and fungus infections.

Do not take atropine, hyoscyamine, methenamine, methylene blue, phenyl salicylate, and benzoic acid within 2 or 3 hours of taking antacids or medicine for diarrhea. Taking antacids or antidiarrhea medicines and atropine, hyoscyamine, methenamine, methylene blue, phenyl salicylate, and benzoic acid too close together may prevent atropine, hyoscyamine, methenamine, methylene blue, phenyl salicylate, and benzoic acid from working properly.

atropine, hyoscyamine, methenamine, methylene blue, phenyl salicylate, and benzoic acid Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

Less common or rare Blurred vision eye pain skin rash or hives Symptoms of overdose Blood in urine and/or stools diarrhea dizziness drowsiness (severe) fast heartbeat flushing or redness of face headache (severe or continuing) lower back pain pain or burning while urinating ringing or buzzing in the ears shortness of breath or troubled breathing sweating unusual tiredness or weakness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common Difficult urination (more common with large doses taken over a prolonged period of time) dryness of mouth, nose, or throat nausea or vomiting stomach upset or pain (more common with large doses taken over a prolonged period of time)

atropine, hyoscyamine, methenamine, methylene blue, phenyl salicylate, and benzoic acid may cause your urine and/or stools to turn blue or blue-green. This is to be expected while you are taking atropine, hyoscyamine, methenamine, methylene blue, phenyl salicylate, and benzoic acid.

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

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aminosalicylic acid


Generic Name: aminosalicylic acid (ah mee no sal i SILL ik)
Brand Names:

What is aminosalicylic acid?

Aminosalicylic acid is an antibiotic. The exact way that aminosalicylic acid works is unknown.

Aminosalicylic acid is used to treat tuberculosis (TB).

Aminosalicylic acid may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about aminosalicylic acid? Take all of the aminosalicylic acid that has been prescribed for you even if you begin to feel better. Your symptoms may begin to improve before the infection is completely treated. Do not take this medicine if it is brown or purple in color or if the package has swollen. This appearance means that the drug has lost its effectiveness. Aminosalicylic acid will turn brown or purple if left in a hot place, if it is kept in direct sunlight, or if it is exposed to water or moisture.

Call your doctor immediately if you experience a fever, a sore throat, unusual bleeding or bruising, or a skin rash.

Who should not take aminosalicylic acid?

Before taking this medication, tell your doctor if you

have ever had an allergic reaction to aminosalicylic acid,

have kidney disease, or

have liver disease.

You may not be able to take aminosalicylic acid, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.

Aminosalicylic acid is in the FDA pregnancy category C. This means that it is not known whether it will harm an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant. It is also not known whether aminosalicylic acid will harm a nursing baby. Do not take this medication without first talking to your doctor if you are breast-feeding a baby. How should I take aminosalicylic acid?

Take aminosalicylic acid exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.

Do not take this medicine if it is brown or purple in color or if the package is swollen. This appearance means that the drug has lost its effectiveness. Aminosalicylic acid will turn brown or purple if left in a hot place, if it is kept in direct sunlight, or if it is exposed to water or moisture.

The granules need to be taken with an acidic food to properly dissolve in your body. They should be sprinkled on top of applesauce or yogurt, or mixed with juice such as tomato, orange, grapefruit, grape, cranberry, apple, or fruit punch. If the granules are mixed with juice, swirl the suspension to ensure mixing and be sure to drink all of the granules.

Granule coatings may appear undissolved in your stools. This is not a cause for concern.

Take all of the aminosalicylic acid that has been prescribed for you even if you begin to feel better. Your symptoms may begin to improve before the infection is completely treated.

Aminosalicylic acid is usually combined with one or more other tuberculosis medicines.

Store the granules in the refrigerator or freezer. This will keep them dry and cool. They can be stored at room temperature for short periods of time if necessary. What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next regularly scheduled dose, skip the missed dose and take the next one as directed. Do not take a double dose of this medication.

What happens if I overdose? Seek emergency medical attention.

Symptoms of an aminosalicylic acid overdose are unknown.

What should I avoid while taking aminosalicylic acid?

There are no restrictions on foods, beverages, or activities during treatment with aminosalicylic acid unless your doctor directs otherwise.

Aminosalicylic acid side effects If you experience any of the following serious side effects, stop taking aminosalicylic acid and seek emergency medical attention:

an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);

a fever;

a sore throat;

unusual bleeding or bruising;

yellow skin or eyes;

a skin rash; or

painful urination.

Other, less serious side effects may be more likely to occur. Continue to take aminosalicylic acid and talk to your doctor if you experience

nausea, vomiting, diarrhea, or abdominal pain; or

undissolved granule coatings in your stools.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect aminosalicylic acid?

Aminosalicylic acid may decrease the amount of digoxin (Lanoxin, Lanoxicaps) that gets absorbed into your body. Higher doses of digoxin may be needed.

Aminosalicylic acid may decrease vitamin B12 absorption, leading to a deficiency. You may need to take a vitamin B12 supplement.

Drugs other then those listed here may also interact with aminosalicylic acid. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

Where can I get more information? Your pharmacist has additional information about aminosalicylic acid written for health professionals that you may read. What does my medicine look like?

Aminosalicylic acid is available with a prescription under the brand name PASER. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

PASER Granules 4 grams--off-white/tan granules


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Sentry AQ Mardel Maracyn-Oxy



Dosage Form: FOR ANIMAL USE ONLY
Medication for Fresh and Saltwater Fish Indications and Usage for Sentry AQ Mardel Maracyn-Oxy

For the treatment and control of the symptoms associated with common bacterial, fungal and viral infections of fresh and saltwater fish.

For true fungal infections of fish and eggs
Effective against common forms of bacterial fin and tail rot. NOTE

Consult a veterinarian or fish expert for assistance in diagnosis of disease causing organisms and treatment options.

DIRECTIONS Use of a hospital tank is recommended.  It is always wise to check your water quality levels to ensure they are within their acceptable ranges before administering any water treatment.  No water changes, pH or temperature adjustments necessary if readings are in ideal range.  Maintain normal filtration and air.  Use 1/2 capfull (2.5 mL) per 10 gallons of water.  Repeat as needed for not more than 5 days.  It is suggested to always increase tank aeration during treatment to ensure an adequate oxygen supply for sick fish.  Switch off UV sterilizers during treatment.  Should fish exhibit signs of distress neutralize the medication by using an aquarium dechlorinator.  Follow the manufacturers directions for dosing. KEEP OUT OF REACH OF CHILDREN
Precautions For aquarium use only.
Warnings Causes irritation.  Avoid contact with eyes, skin and clothing.  If in eyes: Flush eyes with water for 15 minutes.  Call a physician.  If on Skin: Flush skin with water.  (Wash clothing before reuse.)  Wash thoroughly after handling.  THIS PRODUCT IS INTENDED FOR THE EXCLUSIVE USE WITH THE ORNAMENTAL ORGANISMS INDICATED AND IS NOT INTENDED FOR USE WITH HUMANS OR FISH FOR HUMAN CONSUMPTION.  
ACTIVE INGREDIENT Stabilized chlorine oxides
How is Sentry AQ Mardel Maracyn-Oxy Supplied Net Contents 2 fl oz (59 mL)
Net Contents 4 fl oz (118 mL) PACKAGING COMPONENT Sentry AQ Mardel Maracyn-Oxy
Distributed by:
Sergeant's Pet Care Products, Inc., Omaha NE 68130
www.sentrypetcare.com
Sentry AQ Mardel Maracyn-Oxy 
stabilized chlorine oxides  liquid Product Information Product Type OTC ANIMAL DRUG NDC Product Code (Source) 21091-183 Route of Administration EXTRACORPOREAL DEA Schedule      Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength Sodium Chlorite (Chlorous Acid) Sodium Chlorite 43 mg  in 1 mL Inactive Ingredients Ingredient Name Strength No Inactive Ingredients Found Product Characteristics Color yellow (slight yellow tint) Score      Shape Size Flavor Imprint Code Contains          Packaging # NDC Package Description Multilevel Packaging 1 21091-183-04 1 BOTTLE In 1 CARTON contains a BOTTLE, PLASTIC 1 118 mL In 1 BOTTLE, PLASTIC This package is contained within the CARTON (21091-183-04)
Marketing Information Marketing Category Application Number or Monograph Citation Marketing Start Date Marketing End Date unapproved drug other 10/09/2009
Labeler - Sergeant's Pet Care Products, Inc. (876995171) Revised: 01/2010Sergeant's Pet Care Products, Inc.

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Permethrin Cream Rinse


Pronunciation: per-METH-rin
Generic Name: Permethrin
Brand Name: Nix
Permethrin Cream Rinse is used for:

Treating head lice.

Permethrin Cream Rinse is a scabicide. It works by killing lice, although this process is not fully understood. It may attack the nervous system of adult lice or interfere with the development of the eggs they produce.

Do NOT use Permethrin Cream Rinse if: you are allergic to any ingredient in Permethrin Cream Rinse

Contact your doctor or health care provider right away if any of these apply to you.

Before using Permethrin Cream Rinse:

Some medical conditions may interact with Permethrin Cream Rinse. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement if you have allergies to medicines, foods, or other substances

Some MEDICINES MAY INTERACT with Permethrin Cream Rinse. Because little, if any, of Permethrin Cream Rinse is absorbed into the blood, the risk of it interacting with another medicine is low.

Ask your health care provider if Permethrin Cream Rinse may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Permethrin Cream Rinse:

Use Permethrin Cream Rinse as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Before using, wash hair with regular shampoo and towel dry. Apply enough of Permethrin Cream Rinse to saturate hair and scalp, especially behind the ears and on the nape of the neck. Leave on hair for 10 minutes, but no longer. Rinse with water. If live lice are observed after 7 days or more after the first application, treat hair and scalp a second time. Head lice live on the scalp and lay small white eggs (nits) on the hair close to the scalp. For proper head lice management, remove eggs with the comb provided. All personal headgear, scarves, coats, and bed linen should be disinfected by machine washing in hot water and drying. Use the hot cycle of a dryer for at least 20 minutes. Personal articles of clothing or bedding that cannot be washed or dried by machine may be dry cleaned, sealed in a plastic bag for a period of about 2 weeks, or sprayed with a product specifically designed for this purpose. Personal combs and brushes may be disinfected by soaking in hot water above 130 degrees F (54 degrees C) for 5 to 10 minutes. Thoroughly vacuum rooms, including furniture, of individuals infected with lice. If you miss a dose of Permethrin Cream Rinse, use it as soon as you remember. Continue to use it as directed by your doctor.

Ask your health care provider any questions you may have about how to use Permethrin Cream Rinse.

Important safety information: Permethrin Cream Rinse is for external use only. Do not use it near the eyes or allow it to come into contact with the inside of the nose, mouth, or genitals. Irritation may occur if Permethrin Cream Rinse comes into contact with these areas. If Permethrin Cream Rinse gets in your eyes, flush with water immediately. Permethrin Cream Rinse should not be used in CHILDREN younger than 2 months old; safety and effectiveness in these children have not been confirmed. PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Permethrin Cream Rinse while you are pregnant. It is not known if Permethrin Cream Rinse is found in breast milk after topical use. Do not breast-feed while using Permethrin Cream Rinse. Possible side effects of Permethrin Cream Rinse:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Itching; mild burning or stinging; redness; swelling.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Permethrin side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Permethrin Cream Rinse may be harmful if swallowed. Symptoms may include dizziness; headache; loss of appetite; loss of consciousness; seizures; vomiting; weakness.

Proper storage of Permethrin Cream Rinse:

Store Permethrin Cream Rinse at room temperature, between 59 and 77 degrees F (15 and 25 degrees C). Store away from heat, light, and moisture. Keep Permethrin Cream Rinse out of the reach of children and away from pets.

General information: If you have any questions about Permethrin Cream Rinse, please talk with your doctor, pharmacist, or other health care provider. Permethrin Cream Rinse is to be used only by the patient for whom it is prescribed. Do not share it with other people. If your symptoms do not improve or if they become worse, check with your doctor. Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Permethrin Cream Rinse. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012 Database Edition 12.1.1.002 Copyright © 2012 Wolters Kluwer Health, Inc. More Permethrin resources Permethrin Side Effects (in more detail) Permethrin Use in Pregnancy & Breastfeeding Permethrin Support Group 2 Reviews for Permethrin - Add your own review/rating Compare Permethrin with other medications Head Lice Lice Scabies
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Nix Cream Rinse


Pronunciation: per-METH-rin
Generic Name: Permethrin
Brand Name: Nix
Nix Cream Rinse is used for:

Treating head lice.

Nix Cream Rinse is a scabicide. It works by killing lice, although this process is not fully understood. It may attack the nervous system of adult lice or interfere with the development of the eggs they produce.

Do NOT use Nix Cream Rinse if: you are allergic to any ingredient in Nix Cream Rinse

Contact your doctor or health care provider right away if any of these apply to you.

Before using Nix Cream Rinse:

Some medical conditions may interact with Nix Cream Rinse. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement if you have allergies to medicines, foods, or other substances

Some MEDICINES MAY INTERACT with Nix Cream Rinse. Because little, if any, of Nix Cream Rinse is absorbed into the blood, the risk of it interacting with another medicine is low.

Ask your health care provider if Nix Cream Rinse may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Nix Cream Rinse:

Use Nix Cream Rinse as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Before using, wash hair with regular shampoo and towel dry. Apply enough of Nix Cream Rinse to saturate hair and scalp, especially behind the ears and on the nape of the neck. Leave on hair for 10 minutes, but no longer. Rinse with water. If live lice are observed after 7 days or more after the first application, treat hair and scalp a second time. Head lice live on the scalp and lay small white eggs (nits) on the hair close to the scalp. For proper head lice management, remove eggs with the comb provided. All personal headgear, scarves, coats, and bed linen should be disinfected by machine washing in hot water and drying. Use the hot cycle of a dryer for at least 20 minutes. Personal articles of clothing or bedding that cannot be washed or dried by machine may be dry cleaned, sealed in a plastic bag for a period of about 2 weeks, or sprayed with a product specifically designed for this purpose. Personal combs and brushes may be disinfected by soaking in hot water above 130 degrees F (54 degrees C) for 5 to 10 minutes. Thoroughly vacuum rooms, including furniture, of individuals infected with lice. If you miss a dose of Nix Cream Rinse, use it as soon as you remember. Continue to use it as directed by your doctor.

Ask your health care provider any questions you may have about how to use Nix Cream Rinse.

Important safety information: Nix Cream Rinse is for external use only. Do not use it near the eyes or allow it to come into contact with the inside of the nose, mouth, or genitals. Irritation may occur if Nix Cream Rinse comes into contact with these areas. If Nix Cream Rinse gets in your eyes, flush with water immediately. Nix Cream Rinse should not be used in CHILDREN younger than 2 months old; safety and effectiveness in these children have not been confirmed. PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Nix Cream Rinse while you are pregnant. It is not known if Nix Cream Rinse is found in breast milk after topical use. Do not breast-feed while using Nix Cream Rinse. Possible side effects of Nix Cream Rinse:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Itching; mild burning or stinging; redness; swelling.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Nix side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Nix Cream Rinse may be harmful if swallowed. Symptoms may include dizziness; headache; loss of appetite; loss of consciousness; seizures; vomiting; weakness.

Proper storage of Nix Cream Rinse:

Store Nix Cream Rinse at room temperature, between 59 and 77 degrees F (15 and 25 degrees C). Store away from heat, light, and moisture. Keep Nix Cream Rinse out of the reach of children and away from pets.

General information: If you have any questions about Nix Cream Rinse, please talk with your doctor, pharmacist, or other health care provider. Nix Cream Rinse is to be used only by the patient for whom it is prescribed. Do not share it with other people. If your symptoms do not improve or if they become worse, check with your doctor. Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Nix Cream Rinse. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012 Database Edition 12.1.1.002 Copyright © 2012 Wolters Kluwer Health, Inc. More Nix resources Nix Side Effects (in more detail) Nix Use in Pregnancy & Breastfeeding 0 Reviews for Nix - Add your own review/rating Nix Cream Rinse Concise Consumer Information (Cerner Multum) Acticin Concise Consumer Information (Cerner Multum) Acticin Topical Advanced Consumer (Micromedex) - Includes Dosage Information Elimite Prescribing Information (FDA) Compare Nix with other medications Head Lice
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Triveen-CF NAC


Pronunciation: meth-ill-FOE-late/meth-ill-koe-BAL-a-min/a-se-teel-SIS-teen
Generic Name: L-Methylfolate/Methylcobalamin/N-Acetylcysteine
Brand Name: Examples include Cerefolin with NAC and Triveen-CF NAC
Triveen-CF NAC is used for:

Supplying nutritional requirements of certain patients with neurovascular oxidative stress or high blood levels of homocysteine. It may also be used for other conditions as determined by your doctor.

Triveen-CF NAC is a nutritional supplement. It works by providing the body with folate, vitamin B12, and a form of antioxidant, which helps to reduce or eliminate oxidative stress and lower homocysteine levels.

Do NOT use Triveen-CF NAC if: you are allergic to any ingredient in Triveen-CF NAC you are very ill

Contact your doctor or health care provider right away if any of these apply to you.

Before using Triveen-CF NAC:

Some medical conditions may interact with Triveen-CF NAC. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement if you have allergies to medicines, foods, or other substances if you have anemia, liver problems, kidney stones, or a history of ulcers

Some MEDICINES MAY INTERACT with Triveen-CF NAC. Tell your health care provider if you are taking any other medicines, especially any of the following:

Antibiotics (eg, penicillin, cephalexin, ciprofloxacin), cholestyramine, colchicine, colestipol, metformin, nitrous oxide, nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen), para-aminosalicylic acid, potassium chloride, or sulfasalazine because they may decrease the effectiveness of Triveen-CF NAC Fluorouracil or nitrates (eg, nitroglycerin) because their side effects may be increased Barbiturates (eg, phenobarbital), carbamazepine, hydantoins (eg, phenytoin), primidone, pyrimethamine, or valproic acid because their effectiveness may be decreased by Triveen-CF NAC

This may not be a complete list of all interactions that may occur. Ask your health care provider if Triveen-CF NAC may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Triveen-CF NAC:

Use Triveen-CF NAC as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Triveen-CF NAC may be taken with or without food. If you miss a dose of Triveen-CF NAC, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Triveen-CF NAC.

Important safety information: Diabetes patients - Triveen-CF NAC may cause incorrect test results with some ketone tests. Check with your doctor before you adjust the dose of your diabetes medicine or change your diet. Triveen-CF NAC is not recommended for use in CHILDREN younger than 12 years of age. Safety and effectiveness in this age group have not been confirmed. PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Triveen-CF NAC, discuss with your doctor the benefits and risks of using Triveen-CF NAC during pregnancy. Triveen-CF NAC is excreted in breast milk. Do not breastfeed while you are taking Triveen-CF NAC. Possible side effects of Triveen-CF NAC:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Bloated feeling; headache; itching; mild diarrhea; mild fever; nausea; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); lower back or side pain.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Triveen-CF NAC:

Store Triveen-CF NAC at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, light, and moisture. Keep Triveen-CF NAC out of the reach of children and away from pets.

General information: If you have any questions about Triveen-CF NAC, please talk with your doctor, pharmacist, or other health care provider. Triveen-CF NAC is to be used only by the patient for whom it is prescribed. Do not share it with other people. If your symptoms do not improve or if they become worse, check with your doctor. Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Triveen-CF NAC. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012 Database Edition 12.1.1.002 Copyright © 2012 Wolters Kluwer Health, Inc. More Triveen-CF NAC resources Triveen-CF NAC Use in Pregnancy & Breastfeeding Triveen-CF NAC Drug Interactions Triveen-CF NAC Support Group 4 Reviews for Triveen-CF NAC - Add your own review/rating Compare Triveen-CF NAC with other medications Dietary Supplementation Hyperhomocysteinemia
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Vet One Chlorhexidine



Dosage Form: FOR ANIMAL USE ONLY
MWI/Vet One 2% Chlorhexidine solution MWI/Vet One 2% Chlorhexidine solution

ACTIVE INGREDIENTS:
2% Chlorhexidine Gluconate.

CAUTION:
Avoid contact with eyes and mucous membranes. This product is not to be used in ears. If contact is made, flush immediately and thoroughly with clean water. For use on horses and dogs.

Product No. 1CHL008
8CHL008-108
Distributed by:
MWI
Meridian, ID 83680
(888) 694-8381
MWI/Vet One 2% Chlorhexidine solution

PRODUCT DESCRIPION:
A topical aqueous cleaning solution for use on horses and dogs for application to superficial cuts, abrasions or insect stings.

DILUTE:
1 ounce (2 tablespoons) of Chlorhexidine Solution per gallon of clean water.
DIRECTIONS FOR USE:
Rinse skin area to be treated with Chlorhexidine Solution. Wipe away excess and pat dry with sterilized gauze or sponge.
MWI/Vet One 2% Chlorhexidine solution


Vet One Chlorhexidine 
chlorhexidine gluconate  solution Product Information Product Type OTC ANIMAL DRUG NDC Product Code (Source) 13985-017 Route of Administration TOPICAL DEA Schedule      Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength Chlorhexidine Gluconate (CHLORHEXIDINE) Chlorhexidine Gluconate 2 g  in 0.1 L Inactive Ingredients Ingredient Name Strength No Inactive Ingredients Found Product Characteristics Color      Score      Shape Size Flavor Imprint Code Contains          Packaging # NDC Package Description Multilevel Packaging 1 13985-017-80 3.785 L In 1 JUG None
Marketing Information Marketing Category Application Number or Monograph Citation Marketing Start Date Marketing End Date unapproved drug other 01/01/2010
Labeler - MWI VETERINARY SUPPLY CO (019926120) Revised: 01/2010MWI VETERINARY SUPPLY CO

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chondroitin, glucosamine, and methylsulfonylmethane


Generic Name: chondroitin, glucosamine, and methylsulfonylmethane (kon DROI tin, gloo KOSE a meen, and METH il sul FON il METH ane)
Brand names: Glucosamine & Chondroitin with MSM, Glucosamine Chondroitin MSM Complex, Osteo Bi-Flex Advanced, Osteo Bi-Flex Plus MSM, Glucosamine & Chondroitin with MSM

What is chondroitin, glucosamine, and methylsulfonylmethane?

Chondroitin is a naturally occurring substance formed of sugar chains. Chondroitin is believed to help the body maintain fluid and flexibility in the joints.

Glucosamine is a naturally occurring substance that is believed to help develop and renew cartilage (the hard connective tissue mainly located on bones near joints in the body), and keep it lubricated for better joint movement and flexibility.

Methylsulfonylmethane is a naturally occurring form of sulfur that helps support muscles and tendons in the body.

The combination of chondroitin, glucosamine, and methylsulfonylmethane is used to aid in maintaining healthy joints. It is also used as a nutritional supplement in people with osteoarthritis or other inflammatory joint disorders.

Not all uses for chondroitin, glucosamine, and methylsulfonylmethane have been approved by the FDA. Chondroitin, glucosamine, and methylsulfonylmethane should not be used in place of medication prescribed for you by your doctor.

Chondroitin, glucosamine, and methylsulfonylmethane is often sold as an herbal supplement. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination.

Chondroitin, glucosamine, and methylsulfonylmethane may also be used for purposes not listed in this product guide.

What is the most important information I should know about chondroitin, glucosamine, and methylsulfonylmethane? Not all uses for this product have been approved by the FDA. Chondroitin, glucosamine, and methylsulfonylmethane should not be used in place of medication prescribed for you by your doctor.

Chondroitin, glucosamine, and methylsulfonylmethane is often sold as an herbal supplement. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination.

Before using this product, talk to your doctor, pharmacist, herbalist, or other healthcare provider. You may not be able to use chondroitin, glucosamine, and methylsulfonylmethane if you have diabetes, a bleeding or blood clotting disorder such as hemophilia, if you have allergies to certain drugs, if you are overweight, or if you are on a low-salt diet.

Do not take chondroitin, glucosamine, and methylsulfonylmethane without the medical advice if you are using insulin, or a blood thinner such as warfarin (Coumadin, Jantoven). Avoid taking chitosan (usually marketed as a weight-loss product) while you are taking chondroitin, glucosamine, and methylsulfonylmethane. Chitosan can make it harder for your body to absorb chondroitin. What should I discuss with my healthcare provider before taking chondroitin, glucosamine, and methylsulfonylmethane? You should not use this product if you are allergic to it.

Ask a doctor, pharmacist, herbalist, or other healthcare provider if it is safe for you to use this product if you have:

diabetes;

a bleeding or blood clotting disorder such as hemophilia;

if you have allergies to certain drugs;

if you are overweight; or

if you are on a low-salt diet.

It is not known whether chondroitin, glucosamine, and methylsulfonylmethane will harm an unborn baby. Tell your healthcare provider if you are pregnant or plan to become pregnant while using this product. It is not known whether chondroitin, glucosamine, and methylsulfonylmethane passes into breast milk or if it could harm a nursing baby. Do not use this product without telling your healthcare provider if you are breast-feeding a baby. How should I take chondroitin, glucosamine, and methylsulfonylmethane?

When considering the use of herbal supplements, seek the advice of your doctor. You may also consider consulting a practitioner who is trained in the use of herbal/health supplements.

If you choose to use chondroitin, glucosamine, and methylsulfonylmethane, use it as directed on the package or as directed by your doctor, pharmacist, or other healthcare provider. Do not use more of this product than is recommended on the label.

It may take up several weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve after a few weeks of treatment.

Glucosamine may increase the glucose (sugar) levels in your blood. If you have diabetes, you may need to check your blood sugar more often while taking this medication. You may also need to adjust your insulin dosage. Do not change your dose or medication schedule without advice from your doctor.

Chondroitin, glucosamine, and methylsulfonylmethane may be only part of a complete program of treatment that also includes diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely.

Store at room temperature away from moisture, heat, and light. What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while taking chondroitin, glucosamine, and methylsulfonylmethane? Avoid taking chitosan (usually marketed as a weight-loss product) while you are taking chondroitin, glucosamine, and methylsulfonylmethane. Chitosan can make it harder for your body to absorb chondroitin. Chondroitin, glucosamine, and methylsulfonylmethane side effects Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Less serious side effects may include:

mild nausea, upset stomach;

heartburn; or

diarrhea.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect chondroitin, glucosamine, and methylsulfonylmethane?

Tell your doctor about all other medicines you use, especially:

insulin; or

a blood thinner such as warfarin (Coumadin, Jantoven).

This list is not complete and other drugs may interact with chondroitin, glucosamine, and methylsulfonylmethane. Tell your healthcare provider about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More chondroitin, glucosamine, and methylsulfonylmethane resources Chondroitin, glucosamine, and methylsulfonylmethane Drug Interactions Chondroitin, glucosamine, and methylsulfonylmethane Support Group 1 Review for Chondroitin, glucosamine, and methylsulfonylmethane - Add your own review/rating Compare chondroitin, glucosamine, and methylsulfonylmethane with other medications Dietary Supplementation Osteoarthritis Where can I get more information? Consult with a licensed healthcare professional before using any herbal/health supplement. Whether you are treated by a medical doctor or a practitioner trained in the use of natural medicines/supplements, make sure all your healthcare providers know about all of your medical conditions and treatments.
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Hex-Plus


Generic Name: chlorhexidine gluconate liquid
Dosage Form: FOR ANIMAL USE ONLY
Hex-Plus

USE DIRECTIONS:
Use at full strength, do not dilute.


POST-MILKING:
Dip entire teat in Hex-Plus.  Allow to air dry.
If solution in cup becomes visibly dirty.  Then
replenish with Hex-Plus at full strength.  Do
not return unused product to original container.
PROTECT FROM FREEZING
IF FROZEN: SHAKE VIGOROUSLY
AFTER THAWING

WARNING:  CONTAINS CHLORHEXIDINE
GLUCONATE.

Not for human use.
Avoid contamination of food.  Avoid contact
with eyes.  Not for internal use.


OBSERVE LABEL DIRECTIONS

KEEP OUT OF REACH OF CHILDREN!

FIRST AID:
INTERNAL:  If swallowed, do not induce vomiting.
Drink large quantities of water.  See physician immediately.

EYES:  Flush eyes with clear water for 15 minutes.If irritated, obtain medical guidance.
GET MEDICAL ATTENTION IMMEDIATELY.

Hex-Plus

SANITIZING CHLORHEXIDINE TEAT DIP
FORMULATED WITH EMOLLIENTS AND
DERMAL CONDITIONERS


This product, when properly used, is effective as an aid
in reducing the spread of organisms which may cause
mastitis.
Active Ingredient..........1.0% Chlorhexidine Gluconate
Contains 10% Emollient
Lot#:______________________

Exp. Date:___________________

Next Content:________________


Manufactured For:
Tetradyne LLC
PO Box 17003
Reno, NV 89511


Hex-Plus 
teat dip  liquid Product Information Product Type OTC ANIMAL DRUG NDC Product Code (Source) 66399-742 Route of Administration TOPICAL DEA Schedule      Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength CHLORHEXIDINE GLUCONATE (CHLORHEXIDINE) CHLORHEXIDINE GLUCONATE 1.0 L  in 100 L Inactive Ingredients Ingredient Name Strength GLYCERIN 10 L  in 100 L Product Characteristics Color      Score      Shape Size Flavor Imprint Code Contains          Packaging # NDC Package Description Multilevel Packaging 1 66399-742-01 3.78 L In 1 JUG None 2 66399-742-02 18.9 L In 1 PAIL None 3 66399-742-03 56.7 L In 1 DRUM None 4 66399-742-04 113.4 L In 1 DRUM None 5 66399-742-05 207.9 L In 1 DRUM None 6 66399-742-06 945 L In 1 CONTAINER, FLEXIBLE INTERMEDIATE BULK None 7 66399-742-07 1039.5 L In 1 CONTAINER, FLEXIBLE INTERMEDIATE BULK None
Marketing Information Marketing Category Application Number or Monograph Citation Marketing Start Date Marketing End Date unapproved drug other 09/10/2001
Labeler - Tetradyne LLC (130969293) Revised: 11/2010Tetradyne LLC

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Hex-Tra


Generic Name: chlorhexidine gluconate liquid
Dosage Form: FOR ANIMAL USE ONLY
Hex-Tra

USE DIRECTIONS:
Use at full strength, do not dilute.


POST-MILKING:
Dip entire teat in Hex-Tra.  Allow to air dry.
If solution in cup becomes visibly dirty.  Then
replenish with Hex-Tra at full strength.  Do
not return unused product to original container.
PROTECT FROM FREEZING
IF FROZEN: SHAKE VIGOROUSLY
AFTER THAWING

WARNING:  CONTAINS CHLORHEXIDINE
GLUCONATE.

Not for human use.
Avoid contamination of food.  Avoid contact
with eyes.  Not for internal use.


OBSERVE LABEL DIRECTIONS

KEEP OUT OF REACH OF CHILDREN!

FIRST AID:
INTERNAL:  If swallowed, do not induce vomiting.
Drink large quantities of water.  See physician immediately.

EYES:  Flush eyes with clear water for 15 minutes.If irritated, obtain medical guidance.
GET MEDICAL ATTENTION IMMEDIATELY.

Hex-Tra

SANITIZING CHLORHEXIDINE TEAT DIP
FORMULATED WITH EMOLLIENTS AND
DERMAL CONDITIONERS


This product, when properly used, is effective as an aid
in reducing the spread of organisms which may cause
mastitis.
Active Ingredient..........0.50% Chlorhexidine Gluconate
Contains an Emollient System
Lot#:______________________

Exp. Date:___________________

Next Content:________________


Manufactured For:
Tetradyne LLC
PO Box 17003
Reno, NV 89511


Hex-Tra 
teat dip  liquid Product Information Product Type OTC ANIMAL DRUG NDC Product Code (Source) 66399-083 Route of Administration TOPICAL DEA Schedule      Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength CHLORHEXIDINE GLUCONATE (CHLORHEXIDINE) CHLORHEXIDINE GLUCONATE 0.50 L  in 100 L Inactive Ingredients Ingredient Name Strength GLYCERIN 5.0 L  in 100 L Product Characteristics Color      Score      Shape Size Flavor Imprint Code Contains          Packaging # NDC Package Description Multilevel Packaging 1 66399-083-01 3.78 L In 1 JUG None 2 66399-083-02 18.9 L In 1 PAIL None 3 66399-083-03 56.7 L In 1 DRUM None 4 66399-083-04 113.4 L In 1 DRUM None 5 66399-083-05 207.9 L In 1 DRUM None 6 66399-083-06 945 L In 1 CONTAINER, FLEXIBLE INTERMEDIATE BULK None 7 66399-083-07 1039.5 L In 1 CONTAINER, FLEXIBLE INTERMEDIATE BULK None
Marketing Information Marketing Category Application Number or Monograph Citation Marketing Start Date Marketing End Date unapproved drug other 09/10/2001
Labeler - Tetradyne LLC (130969293) Revised: 11/2010Tetradyne LLC

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High Cholesterol Medications


Definition of High Cholesterol: Acquired lipid disorders is a group of disorders characterized by an excess of fatty substances, such as cholesterol, triglycerides, and lipoproteins present in the blood.

Drugs associated with High Cholesterol

The following drugs and medications are in some way related to, or used in the treatment of High Cholesterol. This service should be used as a supplement to, and NOT a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

See sub-topics

Topics under High Cholesterol High Cholesterol, Familial Heterozygous (14 drugs) High Cholesterol, Familial Homozygous (6 drugs) Hyperlipoproteinemia (128 drugs in 6 topics) Hypertriglyceridemia (30 drugs) Niacin Flush (34 drugs) Sitosterolemia (1 drug) Learn more about High Cholesterol

Medical Encyclopedia:

Familial hypercholesterolemia High blood cholesterol levels

Harvard Health Guide:

Symptoms and treatment for High Cholesterol (Hypercholesterolemia)

Drugs.com Health Center:

Cholesterol Center
Drug List: Advicor Altocor Altoprev-Extended-Release-Tablets Atromid-S B-3-50-Nicotinic-Acid B3-500-Gr-Nicotinic-Acid Baycol Choloxin Crestor Evening-Primrose-Oil Fibricor Juvisync Lescol Lescol-Xl-Extended-Release-Tablets Lipitor Livalo Lopid Mevacor Niacin-Sr-Nicotinic-Acid Niacor Niaspan Nicotinex Pravachol Pravigard_Pac Primrose-Oil Simcor Slo-Niacin-Controlled-Release-Capsules Trilipix Vytorin Welchol Zetia Zocor
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Heparin Lock Flush Solution


Generic Name: heparin sodium
Dosage Form: injection, solution
Heparin Lock Flush Solution, USP

FOR MAINTENANCE OF PATENCY OF INTRAVENOUS INJECTION DEVICES ONLY.

NOT FOR ANTICOAGULANT THERAPY.

DERIVED FROM PORCINE INTESTINAL MUCOSA.

PRESERVATIVE FREE.

Heparin Lock Flush Solution Description

Heparin is a heterogeneous group of straight-chain anionic mucopolysaccharides, called glycosaminoglycans having anticoagulant properties. Although others may be present, the main sugars occurring in heparin are: (1) ?-L-iduronic acid 2-sulfate, (2) 2-deoxy-2-sulfamino-?-D-glucose 6-sulfate, (3) ?-D-glucuronic acid, (4) 2-acetamido-2-deoxy-?-D-glucose and (5) ?-L-iduronic acid.  These sugars are present in decreasing amounts, usually in the order (2)> (1)> (4)> (3)> (5), and are joined by glycosidic linkages, forming polymers of varying sizes.  Heparin is strongly acidic because of its content of covalently linked sulfate and carboxylic acid groups.  In heparin sodium, the acidic protons of the sulfate units are partially replaced by sodium ions.

Heparin Lock Flush Solution, USP is a sterile preparation of heparin sodium derived from porcine intestinal mucosa, standardized for anticoagulant activity, with sufficient sodium chloride to make it isotonic with blood.  The potency is determined by a biological assay using a USP reference standard based on units of heparin activity per milligram. 

Structure of Heparin Sodium (representative subunits):

 

Each mL contains: 10 USP Units Heparin sodium (porcine); 9 mg sodium chloride; Water for Injection q.s.  Sodium hydroxide and/or hydrochloric acid for pH adjustment (5.0-7.5).

Each mL contains: 100 USP Units Heparin sodium (porcine); 9 mg sodium chloride; Water for Injection q.s.  Sodium hydroxide and/or hydrochloric acid for pH adjustment (5.0-7.5).

Heparin Lock Flush Solution - Clinical Pharmacology

Heparin inhibits reactions that lead to the clotting of blood and the formation of fibrin clots both in vitro and in vivo.  Heparin acts at multiple sites in the normal coagulation system.  Small amounts of heparin in combination with antithrombin III (heparin cofactor) can inhibit thrombosis by inactivating activated Factor X and inhibiting the conversion of prothrombin to thrombin.  Once active thrombosis has developed, larger amounts of heparin can inhibit further coagulation by inactivating thrombin and preventing the conversion of fibrinogen to fibrin.  Heparin also prevents the formation of a stable fibrin clot by inhibiting the activation of the fibrin stabilizing factor.

Bleeding time is usually unaffected by heparin.  Clotting time is prolonged by full therapeutic doses of heparin; in most cases it is not measurably affected by low doses of heparin.  Loglinear plots of heparin plasma concentrations with time, for a wide range of dose levels, are linear, which suggests the absence of zero order processes.  Liver and the reticulo-endothelial system are the sites of biotransformation.  The biphasic elimination curve, a rapidly declining alpha phase (t?= 10 minutes) and after the age of 40 a slower beta phase, indicates uptake in organs.  The absence of a relationship between anticoagulant half-life and concentration half-life may reflect factors such as protein binding of heparin.

Patients over 60 years of age, following similar doses of heparin, may have higher plasma levels of heparin and longer activated partial thromboplastine times (APTTs) compared with patients under 60 years of age.

Heparin does not have fibrinolytic activity; therefore, it will not lyse existing clots.

Indications and Usage for Heparin Lock Flush Solution

Heparin Lock Flush Solution, USP is intended to maintain patency of an indwelling venipuncture device designed for intermittent injection or infusion therapy or blood sampling.  Heparin Lock Flush Solution may be used following initial placement of the device in the vein, after each injection of a medication or after withdrawal of blood for laboratory tests (see DOSAGE AND ADMINISTRATION, Maintenance of Patency of IV Devices for directions for use).

Heparin Lock Flush Solution is not to be used for anticoagulant therapy.

Contraindications

Heparin sodium should NOT be used in patients with the following conditions: severe thrombocytopenia; an uncontrollable active bleeding state (see WARNINGS), except when this is due to disseminated intravascular coagulation.

Warnings

Heparin is not intended for intramuscular use.

Hypersensitivity

Patients with documented hypersensitivity to heparin should be given the drug only in clearly life-threatening situations (see Adverse Reactions, Hypersensitivity).

Hemorrhage

Hemorrhage can occur at virtually any site in patients receiving heparin.  An unexplained fall in hematocrit, fall in blood pressure or any other unexplained symptom should lead to serious consideration of a hemorrhagic event.

Heparin sodium should be used with extreme caution in infants and in patients with disease states in which there is increased danger of hemorrhage.  Some of the conditions in which increased danger of hemorrhage exists are:

Cardiovascular–Subacute bacterial endocarditis, severe hypertension.

Surgical–During and immediately following (a) spinal tap or spinal anesthesia or (b) major surgery, especially involving the brain, spinal cord or eye.

Hematologic–Conditions associated with increased bleeding tendencies, such as hemophilia, thrombocytopenia and some vascular purpuras.

Gastrointestinal–Ulcerative lesions and continuous tube drainage of the stomach or small intestine.

Other–Menstruation, liver disease with impaired hemostasis.

Thrombocytopenia

Thrombocytopenia has been reported to occur in patients receiving heparin with a reported incidence of 0 to 30%.  Platelet counts should be obtained at baseline.  Mild thrombocytopenia (count greater than 100,000/mm3) may remain stable or reverse even if heparin is continued.  However, thrombocytopenia of any degree should be monitored closely.  If the count falls below 100,000/mm3 or if recurrent thrombosis develops (see Heparin-induced Thrombocytopenia and Heparin-induced Thrombocytopenia and Thrombosis), the heparin product should be discontinued and, if necessary, an alternative anticoagulant administered.

Heparin-induced Thrombocytopenia (HIT) and Heparin-induced Thrombocytopenia and Thrombosis (HITT)

Heparin-induced Thrombocytopenia (HIT) is a serious antibody-mediated reaction resulting from irreversible aggregation of platelets.  HIT may progress to the development of venous and arterial thromboses, a condition referred to as Heparin-induced Thrombocytopenia and Thrombosis (HITT).  Thrombotic events may also be the initial presentation for HITT.  These serious thromboembolic events include deep vein thrombosis, pulmonary embolism, cerebral vein thrombosis, limb ischemia, stroke, myocardial infarction, mesenteric thrombosis, renal arterial thrombosis, skin necrosis, gangrene of the extremities that may lead to amputation, and possibly death.  Thrombocytopenia of any degree should be monitored closely.  If the platelet count falls below 100,000/mm3 or if recurrent thrombosis develops, the heparin product should be promptly discontinued and alternative anticoagulants considered if patients require continued anticoagulation.

Delayed Onset of HIT and HITT

Heparin-induced Thrombocytopenia and Heparin-induced Thrombocytopenia and Thrombosis can occur up to several weeks after the discontinuation of heparin therapy.  Patients presenting with thrombocytopenia or thrombosis after discontinuation of heparin should be evaluated for HIT and HITT.

Use in Neonates

Preservative-Free Heparin Lock Flush Solution, USP should be used for maintaining the patency of intravenous injection devices in neonates.

Precautions General

In infants, the cumulative amounts of heparin received from the frequent administration of Heparin Lock Flush Solution, USP during a 24- hour period should be considered.

Precautions must be exercised when drugs which are incompatible with heparin are administered through an indwelling intravenous catheter containing Heparin Lock Flush Solution, USP (see DOSAGE AND ADMINISTRATION, Maintenance of Patency of IV Devices).

Thrombocytopenia, Heparin-induced Thrombocytopenia (HIT) and Heparin-induced Thrombocytopenia and Thrombosis (HITT)

See WARNINGS.

Increased Risk to Older Patients, Especially Women–A higher incidence of bleeding has been reported in patients, particularly women over 60 years of age.

Laboratory Tests

Periodic platelet counts, hematocrits and tests for occult blood in stool are recommended during the entire course of heparin use (see DOSAGE AND ADMINISTRATION).

Drug Interactions

Platelet Inhibitors–Drugs such as acetylsalicylic acid, dextran, phenylbutazone, ibuprofen, indomethacin, dipyridamole, hydroxychloroquine and others that interfere with platelet-aggregation reactions (the main hemostatic defense of heparinized patients) may induce bleeding and should be used with caution in patients receiving heparin sodium.

Other Interactions–Digitalis, tetracyclines, nicotine or antihistamines may partially counteract the anticoagulant action of heparin sodium.

Carcinogenesis, Mutagenesis, Impairment of Fertility

No long-term studies in animals have been performed to evaluate the carcinogenic potential of heparin.  Also, no reproduction studies in animals have been performed concerning mutagenesis or impairment of fertility.

Pregnancy

Teratogenic Effects: Pregnancy Category C–

Animal reproduction studies have not been conducted with heparin sodium.  It is also not known whether heparin sodium can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity.  Heparin sodium should be given to a pregnant woman only if clearly needed.

Nonteratogenic Effects–Heparin does not cross the placental barrier.

Nursing Mothers

Heparin is not excreted in human milk.

Pediatric Use

Safety and effectiveness in pediatric patients have not been established.  Not for use in neonates (see WARNINGS).

Geriatric Use

A higher incidence of bleeding has been reported in patients over 60 years of age, especially women (see PRECAUTIONS, General and CLINICAL PHARMACOLOGY).

Adverse Reactions Hemorrhage

Hemorrhage is the chief complication that may result from heparin use (see WARNINGS).  An overly prolonged clotting time or minor bleeding during therapy can usually be controlled by withdrawing the drug (see OVERDOSAGE).

Thrombocytopenia, Heparin-induced Thrombocytopenia (HIT) and Heparin-induced Thrombocytopenia and Thrombosis (HITT) and Delayed Onset of HIT and HITT

See WARNINGS.

Local irritation and erythema have been reported with the use of Heparin Lock Flush Solution.

Hypersensitivity

Generalized hypersensitivity reactions have been reported, with chills, fever and urticaria as the most usual manifestations, and asthma, rhinitis, lacrimation, headache, nausea and vomiting, and anaphylactoid reactions, including shock, occurring more rarely.  Itching and burning, especially on the plantar side of the feet, may occur.

Thrombocytopenia has been reported to occur in patients receiving heparin, with a reported incidence of 0 to 30%.  While often mild and of no obvious clinical significance, such thrombocytopenia can be accompanied by severe thromboembolic complications such as skin necrosis, gangrene of the extremities that may lead to amputation, myocardial infarction, pulmonary embolism, stroke, and possibly death (see WARNINGS and PRECAUTIONS).

Certain episodes of painful, ischemic and cyanosed limbs have in the past been attributed to allergic vasospastic reactions.  Whether these are in fact identical to the thrombocytopenia-associated complications remains to be determined.

Overdosage Symptoms

Bleeding is the chief sign of heparin overdosage.  Nosebleeds, blood in urine or tarry stools may be noted as the first sign of bleeding.  Easy bruising or petechial formations may precede frank bleeding.

Treatment - Neutralization of Heparin Effect

When clinical circumstances (bleeding) require reversal of heparinization, protamine sulfate (1% solution) by slow infusion will neutralize heparin sodium.  No more than 50 mg should be administered, very slowly, in any 10 minute period.  Each mg of protamine sulfate neutralizes approximately 100 USP heparin units.  The amount of protamine required decreases over time as heparin is metabolized.  Although metabolism of heparin is complex, it may, for the purpose of choosing a protamine dose, be assumed to have a half-life of about 1/2 hour after intravenous injection.

Administration of protamine sulfate can cause severe hypotensive and anaphylactoid reactions.  Because fatal reactions often resembling anaphylaxis have been reported, the drug should be given only when resuscitation techniques and treatment of anaphylactoid shock are readily available.

For additional information consult the labeling of Protamine Sulfate Injection, USP products.

DOSAGE AND ADMINISTRATION

Parental drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit.  Slight discoloration does not alter potency.

Heparin Lock Flush Solution, USP is not recommended for use in the neonate (see WARNINGS).

Maintenance of Patency of IV Devices

To prevent clot formation in a heparin lock set or central venous catheter following its proper insertion, Heparin Lock Flush Solution, USP is injected via the injection hub in a quantity sufficient to fill the entire device.  This solution should be replaced each time the device is used.  Aspirate before administering any solution via the device in order to confirm patency and location of needle or catheter tip.  If the drug to be administered is incompatible with heparin, the entire device should be flushed with normal saline before and after the medication is administered; following the second saline flush, the Heparin Lock Flush Solution may be reinstilled into the device.  The device manufacturer’s instructions should be consulted for specifics concerning its use.  Usually this dilute heparin solution will maintain anticoagulation within the device for up to 4 hours.

NOTE:  Since repeated injections of small doses of heparin can alter tests for activated partial thromboplastin time (APTT), a baseline value for APTT should be obtained prior to insertion of a heparin lock set.

Withdrawal of Blood Samples

Heparin Lock Flush Solution may also be used after each withdrawal of blood for laboratory tests.  When heparin would interfere with or alter the results of blood tests, the heparin solution should be cleared from the device by aspirating and discarding it before withdrawing the blood sample.

HOW SUPPLIED

Product

No.

NDC

No.

 


504901

63323-549-01

Heparin Lock Flush Solution, USP, Preservative Free, 100 USP Units/mL, 1 mL fill, in a 3 mL flip-top, single dose plastic vial, in packages of 25.

505701

63323-557-01

Heparin Lock Flush Solution, USP, Preservative Free, 10 USP Units/mL, 1 mL fill, in a 3 mL flip-top, single dose plastic vial, in packages of 25.

Unused portion of the vial should be discarded.

Use only if solution is clear and seal intact.


STORAGE

Store at 20° to 25°C (68° to 77°F) [see USP Controlled Room Temperature].

REFERENCES
Tahata T, Shigehito M, Kusuhara K, Ueda Y, et al. Delayed-Onset of Heparin-Induced Thrombocytopenia – A Case Report – J Jpn Assn Torca Surg. 1992;40(3):110-111. Warkentin T, Kelton J. Delayed-Onset Heparin-Induced Thrombocytopenia and Thrombosis. Annals of Internal Medicine. 2001;135:502-506. Rice L, Attisha W, Drexler A, Francis J. Delayed-Onset Heparin-Induced Thrombocytopenia.  Annals of Internal Medicine, 2002;136:210-215. Dieck J., C. Rizo-Patron, et al. (1990). “A New Manifestation and Treatment Alternative for Heparin-Induced Thrombosis.” Chest 98(1524-26). Smythe M, Stephens J, Mattson. Delayed-Onset Heparin-Induced Thrombocytopenia.  Annals of Emergency Medicine, 2005;45(4): 417-419. Divgi A. (Reprint), Thumma S., Hari P., Friedman K. Delayed Onset Heparin-Induced Thrombocytopenia (HIT) Presenting After Undocumented Drug Exposure as Post-Angiography Pulmonary Embolism. Blood.  2003;102(11):127b.

For Product Inquiry: 1-800-551-7176

451198A

Issued: July 2010

PACKAGE LABEL - PRINCIPAL DISPLAY - Heparin Lock Flush Solution 1 mL Single Dose Vial Label

NDC 63323-549-01

504901

Heparin Lock Flush Solution, USP

100 USP Units/mL

(Derived from Porcine Intestinal Mucosa)

Preservative Free                 Rx only

1 mL Single Dose Vial



PACKAGE LABEL - PRINCIPAL DISPLAY - Heparin Lock Flush Solution 1 mL Single Dose Vial Tray Label

NDC 63323-549-01

504901

Heparin Lock Flush Solution, USP

100 USP Units/mL

(Derived from Porcine Intestinal Mucosa)

1 mL Single Dose Vial

Rx only



PACKAGE LABEL - PRINCIPAL DISPLAY - Heparin Lock Flush Solution 1 mL Single Dose Vial

NDC 63323-557-01

505701

Heparin Lock Flush Solution, USP

10 USP Units/mL

(Derived from Porcine Intestinal Mucosa)

Preservative Free                 Rx only

1 mL Single Dose Vial



PACKAGE LABEL - PRINCIPAL DISPLAY - Heparin Lock Flush Solution 1 mL Single Dose Vial Tray Label

NDC 63323-557-01

505701

Heparin Lock Flush Solution, USP

10 USP Units/mL

(Derived from Porcine Intestinal Mucosa)

1 mL Single Dose Vial

Rx only



HEPARIN LOCK FLUSH 
heparin sodium  injection, solution Product Information Product Type HUMAN PRESCRIPTION DRUG NDC Product Code (Source) 63323-557 Route of Administration INTRAVENOUS DEA Schedule      Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength HEPARIN SODIUM (HEPARIN) HEPARIN SODIUM 10 [USP'U]  in 1 mL Inactive Ingredients Ingredient Name Strength SODIUM CHLORIDE 9 mg  in 1 mL SODIUM HYDROXIDE   HYDROCHLORIC ACID   Product Characteristics Color      Score      Shape Size Flavor Imprint Code Contains          Packaging # NDC Package Description Multilevel Packaging 1 63323-557-01 25 VIAL In 1 BOX contains a VIAL 1 1 mL In 1 VIAL This package is contained within the BOX (63323-557-01)
Marketing Information Marketing Category Application Number or Monograph Citation Marketing Start Date Marketing End Date Premarket Notification K092938 08/29/2009
HEPARIN LOCK FLUSH 
heparin sodium  injection, solution Product Information Product Type HUMAN PRESCRIPTION DRUG NDC Product Code (Source) 63323-549 Route of Administration INTRAVENOUS DEA Schedule      Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength HEPARIN SODIUM (HEPARIN) HEPARIN SODIUM 100 [USP'U]  in 1 mL Inactive Ingredients Ingredient Name Strength SODIUM CHLORIDE 9 mg  in 1 mL HYDROCHLORIC ACID   SODIUM HYDROXIDE   Product Characteristics Color      Score      Shape Size Flavor Imprint Code Contains          Packaging # NDC Package Description Multilevel Packaging 1 63323-549-01 25 VIAL In 1 TRAY contains a VIAL 1 1 mL In 1 VIAL This package is contained within the TRAY (63323-549-01)
Marketing Information Marketing Category Application Number or Monograph Citation Marketing Start Date Marketing End Date Premarket Notification K092938 08/12/2009
Labeler - APP Pharmaceuticals, LLC (608775388) Establishment Name Address ID/FEI Operations APP Pharmaceuticals, LLC 840771732 MANUFACTURE Revised: 12/2010APP Pharmaceuticals, LLC More Heparin Lock Flush Solution resources Heparin Lock Flush Solution Dosage Heparin Lock Flush Solution Use in Pregnancy & Breastfeeding Heparin Lock Flush Solution Drug Interactions Heparin Lock Flush Solution Support Group 0 Reviews for Heparin Lock Flush - Add your own review/rating Compare Heparin Lock Flush Solution with other medications Angina Anticoagulation During Pregnancy Antiphospholipid Syndrome Deep Vein Thrombosis Deep Vein Thrombosis, Prophylaxis Heart Attack Pulmonary Embolism Thrombotic/Thromboembolic Disorder
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Usept


Pronunciation: bell-a-DON-a/meth-EN-a-meen/METH-i-leen/FEN-ill sa-LI-si-late
Generic Name: Belladonna Alkaloids/Methenamine/Methylene Blue/Phenyl Salicylate
Brand Name: Examples include Urised and Usept
Usept is used for:

Treating painful and irritating symptoms of the urinary tract due to urinary tract infections or diagnostic procedures.

Usept is a urinary antiseptic, analgesic, and anticholinergic combination. It works by helping to kill bacteria in the urine, decreasing pain and inflammation, and reducing muscle spasms in the urinary tract. These actions work together to help relieve discomfort while urinating.

Do NOT use Usept if: you are allergic to any ingredient in Usept you have had a severe allergic reaction (eg, severe rash, hives, difficulty breathing, dizziness) to aspirin, other salicylate medicines, or a nonsteroidal anti-inflammatory drug (NSAID) (eg, ibuprofen, naproxen, celecoxib) you have angle-closure glaucoma, problems with your esophagus, bowel motility problems, a blockage of your bladder or bowel, severe intestinal problems (eg, ulcerative colitis), severe bleeding, flu or chickenpox, myasthenia gravis, severe kidney problems, or you are severely dehydrated you are taking a sulfonamide (eg, sulfamethizole)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Usept:

Some medical conditions may interact with Usept. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement if you have allergies to medicines, foods, or other substances if you have constipation, diarrhea, an infection of the stomach or bowel, a hiatal hernia, or stomach ulcers if you have nervous system problems, glucose-6-phosphate-dehydrogenase (G-6-PD) deficiency, gout, influenza, Kawasaki syndrome, rheumatic disease, open-angle glaucoma, risk factors for angle-closure glaucoma, kidney or liver problems, an enlarged prostate, bladder problems, or you are unable to urinate if you have a history of stroke or brain blood vessel problems (eg, aneurysm), an irregular heartbeat, heart blood vessel problems, congestive heart failure, heart valve problems, or other heart problems if you are on a low-salt diet

Some MEDICINES MAY INTERACT with Usept. Tell your health care provider if you are taking any other medicines, especially any of the following:

Anticholinergics (eg, benztropine) because the side effects of Usept may be increased Ketoconazole because the effectiveness of Usept may be decreased Monoamine oxidase (MAO) inhibitors or narcotic pain medicine (eg, codeine) because the risk of serious side effects may be increased Medicine for myasthenia gravis (eg, ambenonium), phenothiazines (eg, chlorpromazine), sulfonamides (eg, sulfamethizole), thiazide diuretics (eg, hydrochlorothiazide), or urinary alkalinizers (eg, sodium bicarbonate) because effectiveness may be decreased by Usept

This may not be a complete list of all interactions that may occur. Ask your health care provider if Usept may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Usept:

Use Usept as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Usept may be taken with or without food. Do not take antacids or antidiarrheal medicines (eg, loperamide) within 1 hour before or after taking Usept. Drink plenty of fluids while taking Usept. If you miss a dose of Usept, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Usept.

Important safety information: Usept may cause dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Usept. Using Usept alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks. Do not take Usept more often or in larger amounts than prescribed by your health care provider. Usept may discolor the urine or feces a blue-green color. This is normal and not a cause for concern. Usept contains an aspirin-like medicine, which has been linked to Reye syndrome. Do not give Usept to children or teenagers during or after chickenpox, flu, or other viral infections without checking with your doctor or pharmacist. Use Usept with caution in the ELDERLY because they may be more sensitive to its effects, especially excitement, agitation, drowsiness, and confusion. Usept is not recommended for use in CHILDREN younger than 6 years of age. Safety and effectiveness in this age group have not been confirmed. PREGNANCY and BREAST-FEEDING: It is unknown if Usept can cause harm to the fetus. If you become pregnant while taking Usept, discuss with your doctor the benefits and risks of using Usept during pregnancy. Usept is excreted in breast milk. If you are or will be breast-feeding while you are using Usept, check with your doctor or pharmacist to discuss the risks to your baby. Possible side effects of Usept:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dry mouth; flushing; nausea; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision; difficulty urinating; dizziness; fast or irregular heartbeat.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Usept side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Usept:

Store Usept at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Usept out of the reach of children and away from pets.

General information: If you have any questions about Usept, please talk with your doctor, pharmacist, or other health care provider. Usept is to be used only by the patient for whom it is prescribed. Do not share it with other people. If your symptoms do not improve or if they become worse, check with your doctor. Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Usept. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012 Database Edition 12.1.1.002 Copyright © 2012 Wolters Kluwer Health, Inc. More Usept resources Usept Side Effects (in more detail) Usept Use in Pregnancy & Breastfeeding Usept Drug Interactions Usept Support Group 0 Reviews for Usept - Add your own review/rating Darcalma Prescribing Information (FDA) Darcalma Concise Consumer Information (Cerner Multum) Darpaz Prescribing Information (FDA) Phosenamine Prescribing Information (FDA) Phosphasal Prescribing Information (FDA) Phosphasal Advanced Consumer (Micromedex) - Includes Dosage Information Prosed EC Advanced Consumer (Micromedex) - Includes Dosage Information Urelle Prescribing Information (FDA) Uribel Prescribing Information (FDA) Ustell Prescribing Information (FDA) Compare Usept with other medications Urinary Tract Infection
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Acticin Topical


Generic Name: permethrin (Topical route)

per-METH-rin

Commonly used brand name(s)

In the U.S.

Acticin Elimite Nix Creme Rinse

In Canada

Nix Nix Dermal Cream

Available Dosage Forms:

Lotion Spray Cream Liquid

Therapeutic Class: Pediculicide

Chemical Class: Pyrethroid

Uses For Acticin

Permethrin 1% lotion is used to treat head lice infections. It acts by destroying both the lice and their eggs. The 5% cream is used to treat scabies infections by destroying the mites which cause scabies.

Before Using Acticin

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of topical permethrin in children with use in other age groups.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of topical permethrin in the elderly with use in other age groups.

Pregnancy Pregnancy Category Explanation All Trimesters B Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus. Breast Feeding

Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

The presence of other medical problems may affect the use of topical permethrin. Make sure you tell your doctor if you have other medical problems, especially:

Severe inflammation of the scalp—Use of permethrin may make the condition worse Proper Use of permethrin

This section provides information on the proper use of a number of products that contain permethrin. It may not be specific to Acticin. Please read with care.

Keep this medicine away from the eyes. If you accidentally get some in your eyes, flush them thoroughly with water at once.

Permethrin lotion which is used to treat lice, comes in a container that holds only one treatment. Use as much of the medicine as you need and discard any remaining lotion properly.

For the treatment of head lice (1% lotion):

Shampoo the hair and scalp using regular shampoo. Thoroughly rinse and towel dry the hair and scalp. Allow hair to air dry for a few minutes. Shake the permethrin lotion well before applying. Thoroughly wet the hair and scalp with the permethrin lotion. Be sure to cover the areas behind the ears and on the back of the neck also. Allow the lotion to remain in place for 10 minutes. Then, rinse the hair and scalp thoroughly and dry with a clean towel. When the hair is dry, you may want to comb the hair with a fine-toothed comb to remove any remaining nits (eggs) or nit shells.

Head lice can be easily transferred from one person to another by direct contact with clothing, hats, scarves, bedding, towels, washcloths, hairbrushes and combs, or hairs from infected persons. Therefore, all members of your household should be examined for head lice and should receive treatment if they are found to be infected. If you have any questions about this, check with your doctor.

For the treatment of scabies (5% cream):

Read package directions carefully before using. Thoroughly wash and dry skin. Massage the cream into the skin from the head to the soles of the feet, paying special attention to creases in the skin, hands, feet, between fingers and toes, underarms, and groin. Scabies rarely infests the scalp of adults, although the hairline, neck, side of the head, and forehead may be infested in older people and in infants. Infants should be treated on the scalp, side of the head, and forehead. Leave the permethrin cream on the skin for 8 to 14 hours. Wash off by taking a shower or bath. Change into clean clothes. After treatment, itching may continue for up to 4 weeks. Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For topical dosage forms (cream and lotion): For head lice: Adults and children 2 years of age and older—Apply to the hair and scalp one time. Children up to 2 years of age—Use and dose must be determined by your doctor. For scabies: Adults and children 2 months of age and older—Apply to the skin one time. Children up to 2 months of age—Use and dose must be determined by your doctor. Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using Acticin

To prevent reinfection or spreading of the infection to other people, good health habits are required. These include the following:

Machine wash all clothing (including hats, scarves, and coats), bedding, towels, and washcloths in very hot water and dry them by using the hot cycle of a dryer for at least 20 minutes. Clothing or bedding that cannot be washed should be dry cleaned or sealed in an airtight plastic bag for 2 weeks. Shampoo all wigs and hairpieces. Wash all hairbrushes and combs in very hot soapy water (above 130 °F) for 5 to 10 minutes and do not share them with other people. Clean the house or room by thoroughly vacuuming upholstered furniture, rugs, and floors. Wash all toys in very hot soapy water (above 130 °F) for 5 to 10 minutes or seal in an airtight plastic bag for 2 weeks. This is especially important for stuffed toys used on the bed. Acticin Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common or rare Burning, itching, numbness, rash, redness, stinging, swelling, or tingling of the scalp

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Acticin Topical side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More Acticin Topical resources Acticin Topical Side Effects (in more detail) Acticin Topical Use in Pregnancy & Breastfeeding Acticin Topical Support Group 0 Reviews for Acticin Topical - Add your own review/rating Compare Acticin Topical with other medications Head Lice Lice Scabies
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Quinocort Cream


1. Name Of The Medicinal Product QUINOCORT™ CREAM 2. Qualitative And Quantitative Composition

Potassium Hydroxyquinoline Sulphate BP

0.5%

Hydrocortisone BP

1.0%

3. Pharmaceutical Form

Quinocort Cream is a faintly yellow vanishing cream. It is intended for topical use only.

4. Clinical Particulars 4.1 Therapeutic Indications

The treatment of infected eczema, intertrigo and other steroid-responsive dermatoses where anti-infective cover is appropriate.

4.2 Posology And Method Of Administration

Route of administration: For topical use only.

Adults, children and the elderly

By gentle massage over all the affected area two to three times daily.

4.3 Contraindications

Patients with known sensitivity or intolerance to any of the ingredients.

4.4 Special Warnings And Precautions For Use

Contact with eyes and other mucosal surfaces should be avoided. Caution should be exercised when using this preparation in infants. Long term continuous topical therapy should be avoided in infants - adrenal suppression can occur even without occlusion.

4.5 Interaction With Other Medicinal Products And Other Forms Of Interaction

Not applicable.

4.6 Pregnancy And Lactation

In pregnant animals administration of corticosteroids can cause abnormalities of foetal development. The relevance of this finding in human beings has not been established. However, topical steroids should not be used extensively in pregnancy i.e. in large amounts for long periods.

4.7 Effects On Ability To Drive And Use Machines

Not applicable.

4.8 Undesirable Effects

Not applicable.

4.9 Overdose

Not applicable.

5. Pharmacological Properties

Hydrocortisone provides anti-inflammatory action yet is the least potent topical corticosteroid available. Potassium hydroxyquinoline sulphate provides broad spectrum antibacterial and anticandidal activity. The combination facilitates treatment of steroid-responsive dermatoses where complication by infection with bacteria or yeasts is evident suspected, or a possibility.

6. Pharmaceutical Particulars 6.1 List Of Excipients

Lactic Acid BP, White Soft Paraffin BP, Edetic Acid BP, Sodium Acid Phosphate BP, Maize Starch BP, cetyl stearyl alcohol, sodium cetyl stearyl sulphate, PEG 40 castor oil, Chlorocresol BP, Purified Water BP.

6.2 Incompatibilities

Not applicable.

6.3 Shelf Life

Two years.

6.4 Special Precautions For Storage

Quinocort Cream should be stored in a cool, dry place avoiding extremes of temperature i.e. not less than 5°C and not more than 30°C.

6.5 Nature And Contents Of Container

Quinocort Cream is available in heat sealed low density polyethylene tubes with flush fitting cap containing 30 g of product. Each tube is cartoned and contains a patient information leaflet.

6.6 Special Precautions For Disposal And Other Handling

For topical use only.

8. Marketing Authorisation Number(S)

0291/0014.

10. Date Of Revision Of The Text

May 1995.

Legal category

POM.


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