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Clear Up Prep



Dosage Form: gel
Drug Facts ACTIVE INGREDIENT

Salicylic Acid 2% w/w.

INACTIVE INGREDIENTS

WATER • SORBITOL • ETHOXYDIGLYCOL • GLYCOLIC ACID • METHYL GLUCETH-20 • SODIUM CITRATE • GLYCERIN • LACTIC ACID • SODIUM HYDROXIDE • CELLULOSE GUM • XANTHAN GUM • ETHYLHEXYLGLYCERIN • PROPYLENE GLYCOL • PHENOXYETHANOL • CITRUS MEDICA LIMONUM (LEMON) FRUIT EXTRACT • HEDERA HELIX (IVY) EXTRACT • SAPONARIA OFFICINALIS EXTRACT •
ARCTIUM LAPPA ROOT EXTRACT • SALVIA OFFICINALIS (SAGE) LEAF EXTRACT •

DIRCETIONS

Cover the eyes with cotton pads soaked in Blue Water. With the fingertips, apply evenly to the face and neck Clear Up Prep Lotion, making sure to avoid the lips.

Application: 2-3 minutes | Pause: 7-8 minutes

WARNINGS

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image of carton label
image of tube 5ml label

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Keep out of reach of children.

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Clear Up Prep 
salicylic acid  gel Product Information Product Type HUMAN OTC DRUG NDC Product Code (Source) 62499-395 Route of Administration TOPICAL DEA Schedule      Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength SALICYLIC ACID (SALICYLIC ACID) SALICYLIC ACID 2 g  in 100 g Inactive Ingredients Ingredient Name Strength WATER   SORBITOL   DIETHYLENE GLYCOL MONOETHYL ETHER   GLYCOLIC ACID   METHYL GLUCETH-20   SODIUM CITRATE   GLYCERIN   LACTIC ACID   SODIUM HYDROXIDE   PROPYLENE GLYCOL   PHENOXYETHANOL   CARBOXYMETHYLCELLULOSE SODIUM   XANTHAN GUM   ETHYLHEXYLGLYCERIN   LEMON OIL   SAPONARIA OFFICINALIS ROOT   ARCTIUM LAPPA ROOT   SAGE OIL   Product Characteristics Color blue (dark bleu) Score      Shape Size Flavor Imprint Code Contains          Packaging # NDC Package Description Multilevel Packaging 1 62499-395-11 1 TUBE In 1 CARTON contains a TUBE (62499-395-10) 1 62499-395-10 5 g In 1 TUBE This package is contained within the CARTON (62499-395-11)
Marketing Information Marketing Category Application Number or Monograph Citation Marketing Start Date Marketing End Date OTC monograph final part358H 07/01/2010
Labeler - Laboratoire Dr. Renaud (202501565) Revised: 07/2010Laboratoire Dr. Renaud
More Clear Up Prep resources Clear Up Prep Side Effects (in more detail) Clear Up Prep Use in Pregnancy & Breastfeeding Clear Up Prep Drug Interactions Clear Up Prep Support Group 1 Review for Clear Up Prep - Add your own review/rating Compare Clear Up Prep with other medications Acne Dermatological Disorders Warts
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All Clear AR Drops


Pronunciation: na-FAZ-oh-leen
Generic Name: Naphazoline
Brand Name: Examples include All Clear and Clear Eyes
All Clear AR Drops are used for:

Temporarily relieving redness, burning, and irritation caused by dry eyes. It may also be used for other conditions as determined by your doctor.

All Clear AR Drops are an eye decongestant and lubricant. It works by constricting the blood vessels in the eye and coating the eye, which relieves redness, dryness, and irritation.

Do NOT use All Clear AR Drops if: you are allergic to any ingredient in All Clear AR Drops you have taken furazolidone or a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the past 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using All Clear AR Drops:

Some medical conditions may interact with All Clear AR Drops. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement if you have allergies to medicines, foods, or other substances if you have glaucoma, high blood pressure, diabetes, heart problems, or thyroid problems, or you are taking medicine for high blood pressure

Some MEDICINES MAY INTERACT with All Clear AR Drops. Tell your health care provider if you are taking any other medicines, especially any of the following:

Tricyclic antidepressants (eg, amitriptyline) because they may decrease All Clear AR Drops's effectiveness Cocaine, furazolidone, MAO inhibitors (eg, phenelzine), or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of All Clear AR Drops's side effects, such as headache, fever, and high blood pressure Bromocriptine or cocaine because their actions and side effects may be increased by All Clear AR Drops

This may not be a complete list of all interactions that may occur. Ask your health care provider if All Clear AR Drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use All Clear AR Drops:

Use All Clear AR Drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.

All Clear AR Drops are for use in the eye only. Avoid contact with the nose, mouth, or other mucous membranes. To use All Clear AR Drops, first, wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eye for 1 to 2 minutes. Do not blink. Remove excess medicine around your eye with a clean tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them. To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including your eye. Keep the container tightly closed. If you miss a dose of All Clear AR Drops and you are using it regularly, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Ask your health care provider any questions you may have about how to use All Clear AR Drops.

Important safety information: Remove contact lenses before using All Clear AR Drops. Do not use All Clear AR Drops if it becomes cloudy or changes color. Contact your doctor if you experience changes in vision, eye pain, irritation, soreness, or continued redness, or if your condition does not improve after 3 days. Use All Clear AR Drops with caution in CHILDREN because they may be more sensitive to its effects. PREGNANCY and BREAST-FEEDING: If you become pregnant while taking All Clear AR Drops, discuss with your doctor the benefits and risks of using All Clear AR Drops during pregnancy. It is unknown if All Clear AR Drops are excreted in breast milk. If you are or will be breast-feeding while you are using All Clear AR Drops, check with your doctor or pharmacist to discuss the risks to your baby. Possible side effects of All Clear AR Drops:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Blurred vision; minor stinging when the medicine is dropped into the eye.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); changes in vision; eye pain; worsening or persistent eye irritation or redness.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: All Clear AR side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. All Clear AR Drops may be harmful if swallowed, especially in children.

Proper storage of All Clear AR Drops:

Store All Clear AR Drops at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep All Clear AR Drops out of the reach of children and away from pets.

General information: If you have any questions about All Clear AR Drops, please talk with your doctor, pharmacist, or other health care provider. All Clear AR Drops are to be used only by the patient for whom it is prescribed. Do not share it with other people. If your symptoms do not improve or if they become worse, check with your doctor. Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about All Clear AR Drops. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012 Database Edition 12.1.1.002 Copyright © 2012 Wolters Kluwer Health, Inc. More All Clear AR resources All Clear AR Side Effects (in more detail) All Clear AR Use in Pregnancy & Breastfeeding All Clear AR Drug Interactions All Clear AR Support Group 0 Reviews for All Clear AR - Add your own review/rating Compare All Clear AR with other medications Eye Dryness/Redness Eye Redness/Itching
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Clear Eyes Extra Relief Drops


Pronunciation: na-FAZ-oh-leen
Generic Name: Naphazoline
Brand Name: Examples include All Clear and Clear Eyes
Clear Eyes Extra Relief Drops are used for:

Temporarily relieving redness, burning, and irritation caused by dry eyes. It may also be used for other conditions as determined by your doctor.

Clear Eyes Extra Relief Drops are an eye decongestant and lubricant. It works by constricting the blood vessels in the eye and coating the eye, which relieves redness, dryness, and irritation.

Do NOT use Clear Eyes Extra Relief Drops if: you are allergic to any ingredient in Clear Eyes Extra Relief Drops you have taken furazolidone or a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the past 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Clear Eyes Extra Relief Drops:

Some medical conditions may interact with Clear Eyes Extra Relief Drops. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement if you have allergies to medicines, foods, or other substances if you have glaucoma, high blood pressure, diabetes, heart problems, or thyroid problems, or you are taking medicine for high blood pressure

Some MEDICINES MAY INTERACT with Clear Eyes Extra Relief Drops. Tell your health care provider if you are taking any other medicines, especially any of the following:

Tricyclic antidepressants (eg, amitriptyline) because they may decrease Clear Eyes Extra Relief Drops's effectiveness Cocaine, furazolidone, MAO inhibitors (eg, phenelzine), or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of Clear Eyes Extra Relief Drops's side effects, such as headache, fever, and high blood pressure Bromocriptine or cocaine because their actions and side effects may be increased by Clear Eyes Extra Relief Drops

This may not be a complete list of all interactions that may occur. Ask your health care provider if Clear Eyes Extra Relief Drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Clear Eyes Extra Relief Drops:

Use Clear Eyes Extra Relief Drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Clear Eyes Extra Relief Drops are for use in the eye only. Avoid contact with the nose, mouth, or other mucous membranes. To use Clear Eyes Extra Relief Drops, first, wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eye for 1 to 2 minutes. Do not blink. Remove excess medicine around your eye with a clean tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them. To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including your eye. Keep the container tightly closed. If you miss a dose of Clear Eyes Extra Relief Drops and you are using it regularly, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Ask your health care provider any questions you may have about how to use Clear Eyes Extra Relief Drops.

Important safety information: Remove contact lenses before using Clear Eyes Extra Relief Drops. Do not use Clear Eyes Extra Relief Drops if it becomes cloudy or changes color. Contact your doctor if you experience changes in vision, eye pain, irritation, soreness, or continued redness, or if your condition does not improve after 3 days. Use Clear Eyes Extra Relief Drops with caution in CHILDREN because they may be more sensitive to its effects. PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Clear Eyes Extra Relief Drops, discuss with your doctor the benefits and risks of using Clear Eyes Extra Relief Drops during pregnancy. It is unknown if Clear Eyes Extra Relief Drops are excreted in breast milk. If you are or will be breast-feeding while you are using Clear Eyes Extra Relief Drops, check with your doctor or pharmacist to discuss the risks to your baby. Possible side effects of Clear Eyes Extra Relief Drops:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Blurred vision; minor stinging when the medicine is dropped into the eye.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); changes in vision; eye pain; worsening or persistent eye irritation or redness.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Clear Eyes Extra Relief side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Clear Eyes Extra Relief Drops may be harmful if swallowed, especially in children.

Proper storage of Clear Eyes Extra Relief Drops:

Store Clear Eyes Extra Relief Drops at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Clear Eyes Extra Relief Drops out of the reach of children and away from pets.

General information: If you have any questions about Clear Eyes Extra Relief Drops, please talk with your doctor, pharmacist, or other health care provider. Clear Eyes Extra Relief Drops are to be used only by the patient for whom it is prescribed. Do not share it with other people. If your symptoms do not improve or if they become worse, check with your doctor. Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Clear Eyes Extra Relief Drops. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012 Database Edition 12.1.1.002 Copyright © 2012 Wolters Kluwer Health, Inc. More Clear Eyes Extra Relief resources Clear Eyes Extra Relief Side Effects (in more detail) Clear Eyes Extra Relief Use in Pregnancy & Breastfeeding Clear Eyes Extra Relief Drug Interactions Clear Eyes Extra Relief Support Group 0 Reviews for Clear Eyes Extra Relief - Add your own review/rating Compare Clear Eyes Extra Relief with other medications Eye Dryness/Redness Eye Redness/Itching
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Norditropin Simplexx 10mg / 1.5ml


Norditropin SimpleXx 10 mg/1.5 ml

solution for injection in cartridges

Somatropin

Read all of this leaflet carefully before you start using this medicine.

Keep this leaflet. You may need to read it again. If you have further questions, ask your doctor or pharmacist. This medicine has been prescribed for you personally. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours. If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.

In this leaflet: 1. What Norditropin SimpleXx is and what it is used for 2. Before you use Norditropin SimpleXx 3. How to use Norditropin SimpleXx 4. Possible side effects 5. How to store Norditropin SimpleXx 6. Further information. What Norditropin SimpleXx is and what it is used for

Norditropin SimpleXx contains a biosynthetic human growth hormone called somatropin which is identical to the growth hormone produced naturally in the body. Children need growth hormone to help them grow, but adults also need it for their general health.

Norditropin SimpleXx comes as a solution in a cartridge ready for you to inject after you have put it in the matching NordiPen injection pen.

Norditropin SimpleXx is used to treat growth failure in children:

If they have no or very low production of growth hormone If they have Turner syndrome (a genetic problem which may affect growth) If they have reduced kidney function If they are short and were born small for gestational age (SGA).

Norditropin SimpleXx is used as a growth hormone replacement in adults:

In adults Norditropin SimpleXx is used to replace growth hormone if their growth hormone production has been decreased since childhood or has been lost in adulthood because of a tumour, treatment of a tumour or a disease that affects the gland which produces growth hormone.

Before you use Norditropin SimpleXx Do not use Norditropin SimpleXx If you are allergic (hypersensitive) to somatropin, to phenol or to any of the other ingredients of Norditropin SimpleXx (listed in section 6, Further information) If you have had a kidney transplant If you are pregnant or breast-feeding (See pregnancy and breast-feeding) If you have a cancer, a tumour or are still in anti-tumour therapy If you have an acute critical illness e.g. open heart surgery, abdominal surgery, multiple accidental trauma or acute respiratory failure. Take special care with Norditropin SimpleXx If you have diabetes If you have ever had a cancer or another kind of tumour If you have recurrent headaches, eyesight problems, nausea or if vomiting occurs If you have abnormal thyroid function If you develop scoliosis If you are over 60 years of age, or have received somatropin treatment as an adult for more than 5 years, as experience is limited If you suffer from kidney disease your kidney function should be monitored by your physician.

Tell your doctor if any of these apply to you as Norditropin SimpleXx may not be suitable.

Using other medicines

Your doctor needs to know if you are already being treated with:

Glucocorticoids or sex steroids – your adult height may be affected if you use Norditropin SimpleXx and glucocorticoids or sex steroids at the same time Insulin - as your dose may need to be adjusted Thyroid hormone.

Tell your doctor or pharmacist if you are taking other medicines or have recently taken any. This includes medicines obtained without a prescription.

Pregnancy and breast-feeding Pregnancy. Stop the treatment and tell your doctor if you become pregnant while you are using Norditropin SimpleXx Breast-feeding. Do not use Norditropin SimpleXx while you are breast-feeding as somatropin might pass into your milk. Driving and using machines

Norditropin SimpleXx does not affect the use of any machines or the ability to drive safely.

How to use Norditropin SimpleXx

Always use Norditropin SimpleXx exactly as your doctor has told you. Check with your doctor or pharmacist if you are unsure.

Usual dose

The dose for children depends on their body weight and body surface area. The adult dose depends on height, weight, gender and growth hormone sensitivity and will be adjusted until you are on the right dose.

Children with low production or lack of growth hormone: The usual dose is 25 to 35 microgram per kg body weight per day or 0.7 to 1.0 mg per m? body surface area per day. Children with Turner syndrome: The usual dose is 45 to 67 microgram per kg body weight per day or 1.3 to 2.0 mg per m? body surface area per day. Children with kidney disease: The usual dose is 50 microgram per kg body weight per day or 1.4 mg per m? body surface area per day. Children born small for gestational age (SGA): The usual dose is 35 microgram per kg body weight per day or 1.0 mg per m? body surface area per day until final height is reached. (In clinical trials of short children born SGA doses of 33 and 67 microgram per kg body weight per day have typically been used.) Adults with low production or lack of growth hormone: The usual starting dose is 0.1 to 0.3 mg per day. Your doctor will increase this dose each month until you are on the right dose. The usual maximum dose is 1.0 mg per day. When to use Norditropin SimpleXx Inject your daily dose into the skin every evening just before bedtime. Using the cartridges to inject yourself Norditropin SimpleXx solution comes in cartridges ready to be used in the matching NordiPen. The NordiPen instruction manual tells you how to use the cartridges in the injection pen Check each new Norditropin SimpleXx cartridge before you use it. Do not use any cartridge that is damaged or cracked Only use a Norditropin SimpleXx cartridge if the solution inside is clear and colourless Vary the area you inject so you do not harm your skin Do not share your Norditropin SimpleXx cartridge with anyone else. How long you will need treatment for If you are using Norditropin SimpleXx for growth failure because of Turner syndrome, a kidney disease or if you were born small for gestational age (SGA), continue using Norditropin SimpleXx until you stop growing If you lack growth hormone, continue using Norditropin SimpleXx into adulthood Do not stop using Norditropin SimpleXx without discussing it with your doctor first. If you use too much: Tell your doctor if you inject too much Norditropin SimpleXx. Long-term overdosing can cause abnormal growth and coarsening of facial features. If you forget a dose: Take the next dose as usual, at the normal time. Do not take a double dose to make up for a forgotten dose. Possible side effects

Like all medicines, Norditropin SimpleXx can cause side effects, although not everybody gets them.

Very rare effects in children and adults

(may affect up to 1 in 10,000 people):

Rash; wheezing; swollen eyelids, face or lips; complete collapse. Any of these may be signs of allergic reactions Headache, eyesight problems, feeling sick (nausea) and being sick (vomiting).
These may be signs of raised pressure in the brain Serum thyroxin levels may decrease

If you get any of these effects, see a doctor as soon as possible. Stop using Norditropin SimpleXx until your doctor says you can continue treatment.

Formation of antibodies directed against somatropin has been rarely observed during Norditropin therapy.

Cases of leukaemia and relapse of brain tumours have also been reported in patients treated with somatropin (the active ingredient in Norditropin SimpleXx), although there is no evidence that somatropin was responsible.

If you think you are suffering from any of these diseases, speak to your doctor.

Other side effects in children:

Uncommon effects

(may affect up to 1 in 100 children):

Headache Redness, itching and pain in the area of injection.

Rare effects

(may affect up to 1 in 1000 children):

Rash Muscle and joint pain Swollen hands and feet due to fluid retention.

In rare cases, children using Norditropin SimpleXx have experienced hip and knee pain or have started limping. These symptoms may be caused by a disease affecting the top of the thigh bone (Legg-Calv? disease) or because the end of the bone has slipped from the cartilage (slipped capital femoral epiphysis) and may not be due to Norditropin SimpleXx.

In children with Turner syndrome, a few cases of increased growth of hands and feet compared to height have been observed in clinical trials.

A clinical trial in children with Turner syndrome has shown that high doses of Norditropin can possibly increase the risk of getting ear infections.

Other side effects in adults:

Very common effects

(may affect more than 1 in 10 adults):

Swollen hands and feet due to fluid retention.

Common effects

(may affect up to 1 in 10 adults):

Headache Feeling of skin crawling (formication) and numbness or pain mainly in fingers Joint pain and stiffness; muscle pain.

Uncommon effects

(may affect up to 1 in 100 adults):

Type 2 diabetes Carpal tunnel syndrome tingling and pain in fingers and hands Itching (can be intense) and pain in the area of injection Muscle stiffness.

If any of these side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist, as you may need to reduce your dose.

How to store Norditropin SimpleXx

Keep out of the reach and sight of children.

Do not use Norditropin SimpleXx after the expiry date which is stated on the package.

The expiry date refers to the last day of that month.

Store unused Norditropin SimpleXx cartridges in a refrigerator (2°C to 8°C) in the outer carton, in order to protect from light. Do not freeze or expose to heat.

After starting to use a Norditropin SimpleXx 10 mg/1.5 ml cartridge in an injection pen you can either:

Keep it in the pen for up to 4 weeks in a refrigerator (2°C and 8°C), or Keep it in the pen for up to 3 weeks at room temperature (below 25°C).

Do not continue to use Norditropin SimpleXx cartridges which have been frozen or exposed to excessive temperatures.

Check each new Norditropin SimpleXx cartridge before you use it. Do not use any cartridge that is damaged or cracked.

Do not use any Norditropin SimpleXx cartridge if the solution inside is not clear and colourless.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

Further information What Norditropin SimpleXx contains The active substance is somatropin The solution also contains mannitol; histidine; poloxamer 188; phenol; water for injections; hydrochloric acid and sodium hydroxide. What Norditropin SimpleXx looks like and contents of the pack

Norditropin SimpleXx is a clear and colourless solution in a 1.5 ml glass cartridge ready for injection in the NordiPen injection pen.

1 ml of solution contains 6.7 mg somatropin.

1 mg of somatropin corresponds to 3 IU of somatropin.

Norditropin SimpleXx is available in three strengths:

5 mg/1.5 ml, 10 mg/1.5 ml and 15 mg/1.5 ml (equivalent to 3.3 mg/ml, 6.7 mg/ml and 10 mg/ml, respectively).

Manufacturer

Norditropin SimpleXx is made by:

Novo Nordisk A/S Novo All? DK-2880 Bagsv?rd Denmark Marketing authorisation holder Novo Nordisk Limited Broadfield Park Brighton Road Crawley West Sussex RH11 9RT UK

This leaflet was last approved in 02/2010.

Norditropin and SimpleXx are Trademarks owned by Novo Nordisk Health Care AG Switzerland

NordiPen is a trademark owned by Novo Nordisk A/S, Denmark

© 1999 / 2008

8-2071-01-002-4


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Citrucel Lax


Generic Name: methylcellulose (METH il SEL yoo los)
Brand Names: Citrucel, Citrucel Clear Mix, Citrucel Food Pack, Citrucel Lax, Citrucel SF

What is Citrucel Lax (methylcellulose)?

Methylcellulose is a bulk-forming laxative. Methylcellulose absorbs liquid in the intestines and makes a bulky, softer stool which is easier to pass.

Methylcellulose helps relieve constipation and to maintain regularity.

Methylcellulose may also have uses other than those listed in this product guide.

What is the most important information I should know about Citrucel Lax (methylcellulose)? Do not use methylcellulose without first talking to your doctor if you have stomach (abdominal) pain, nausea, vomiting, or difficulty swallowing. Taking methylcellulose without enough liquid may cause it to swell in the throat and cause choking. If you experience chest pain, vomiting, difficulty swallowing, or difficulty breathing after taking methylcellulose, seek immediate medical attention. What should I discuss with my healthcare provider before taking Citrucel Lax (methylcellulose)? Do not take methylcellulose without first talking to your doctor if you have

stomach (abdominal) pain, nausea, or vomiting;

difficulty swallowing; or

intestinal obstruction or fecal impaction.

You may not be able to take methylcellulose or you may require special monitoring while taking methylcellulose if you have any of the conditions listed above.

Each level scoop of sugar-free methylcellulose powder contains 52 mg of phenylalanine. Individuals with phenylketonuria may need to monitor their intake of this additive.

Talk to your doctor before taking methylcellulose if you are pregnant or breast-feeding a baby. How should I take Citrucel Lax (methylcellulose)?

Take methylcellulose exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take methylcellulose capsules with a full glass (at least 8 ounces) of water or another liquid.

Mix methylcellulose powder with at least 8 ounces of water or another noncarbonated beverage. Mix briskly and drink promptly.

Taking methylcellulose without enough liquid may cause it to swell in the throat and cause choking.

If methylcellulose has produced no effect within one week or if rectal bleeding occurs, stop taking methylcellulose and contact your doctor. Do not take more methylcellulose than is recommended or for longer than one week except under the direction of your doctor.

If you experience chest pain, vomiting, difficulty swallowing, or difficulty breathing after taking methylcellulose, seek immediate medical attention. Store methylcellulose at room temperature away from moisture and heat. What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose.

What happens if I overdose? Seek emergency medical attention if an overdose is suspected.

Symptoms of a methylcellulose overdose are not known.

What should I avoid while taking Citrucel Lax (methylcellulose)?

There are no restrictions on foods, beverages, or activities during treatment with methylcellulose unless otherwise directed by your healthcare provider.

Citrucel Lax (methylcellulose) side effects If you experience any of the following uncommon but serious side effects, stop taking methylcellulose and seek medical treatment or contact your doctor immediately:

an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);

chest pain;

difficulty swallowing;

rectal bleeding; or

severe abdominal pain, nausea or vomiting.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Citrucel Lax (methylcellulose)?

Methylcellulose can interact with other medications. Before taking methylcellulose, talk to your doctor if you are taking any prescription or over-the-counter medicines. You may not be able to take methylcellulose, or you may require a dosage adjustment or special monitoring if you are taking any other medicines.

More Citrucel Lax resources Citrucel Lax Side Effects (in more detail) Citrucel Lax Use in Pregnancy & Breastfeeding Citrucel Lax Drug Interactions Citrucel Lax Support Group 0 Reviews for Citrucel Lax - Add your own review/rating Citrucel Prescribing Information (FDA) Citrucel MedFacts Consumer Leaflet (Wolters Kluwer) Compare Citrucel Lax with other medications Constipation Where can I get more information? Your pharmacist has more information about methylcellulose written for health professionals that you may read.

See also: Citrucel Lax side effects (in more detail)


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Triveen-CF NAC


Pronunciation: meth-ill-FOE-late/meth-ill-koe-BAL-a-min/a-se-teel-SIS-teen
Generic Name: L-Methylfolate/Methylcobalamin/N-Acetylcysteine
Brand Name: Examples include Cerefolin with NAC and Triveen-CF NAC
Triveen-CF NAC is used for:

Supplying nutritional requirements of certain patients with neurovascular oxidative stress or high blood levels of homocysteine. It may also be used for other conditions as determined by your doctor.

Triveen-CF NAC is a nutritional supplement. It works by providing the body with folate, vitamin B12, and a form of antioxidant, which helps to reduce or eliminate oxidative stress and lower homocysteine levels.

Do NOT use Triveen-CF NAC if: you are allergic to any ingredient in Triveen-CF NAC you are very ill

Contact your doctor or health care provider right away if any of these apply to you.

Before using Triveen-CF NAC:

Some medical conditions may interact with Triveen-CF NAC. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement if you have allergies to medicines, foods, or other substances if you have anemia, liver problems, kidney stones, or a history of ulcers

Some MEDICINES MAY INTERACT with Triveen-CF NAC. Tell your health care provider if you are taking any other medicines, especially any of the following:

Antibiotics (eg, penicillin, cephalexin, ciprofloxacin), cholestyramine, colchicine, colestipol, metformin, nitrous oxide, nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen), para-aminosalicylic acid, potassium chloride, or sulfasalazine because they may decrease the effectiveness of Triveen-CF NAC Fluorouracil or nitrates (eg, nitroglycerin) because their side effects may be increased Barbiturates (eg, phenobarbital), carbamazepine, hydantoins (eg, phenytoin), primidone, pyrimethamine, or valproic acid because their effectiveness may be decreased by Triveen-CF NAC

This may not be a complete list of all interactions that may occur. Ask your health care provider if Triveen-CF NAC may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Triveen-CF NAC:

Use Triveen-CF NAC as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Triveen-CF NAC may be taken with or without food. If you miss a dose of Triveen-CF NAC, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Triveen-CF NAC.

Important safety information: Diabetes patients - Triveen-CF NAC may cause incorrect test results with some ketone tests. Check with your doctor before you adjust the dose of your diabetes medicine or change your diet. Triveen-CF NAC is not recommended for use in CHILDREN younger than 12 years of age. Safety and effectiveness in this age group have not been confirmed. PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Triveen-CF NAC, discuss with your doctor the benefits and risks of using Triveen-CF NAC during pregnancy. Triveen-CF NAC is excreted in breast milk. Do not breastfeed while you are taking Triveen-CF NAC. Possible side effects of Triveen-CF NAC:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Bloated feeling; headache; itching; mild diarrhea; mild fever; nausea; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); lower back or side pain.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Triveen-CF NAC:

Store Triveen-CF NAC at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, light, and moisture. Keep Triveen-CF NAC out of the reach of children and away from pets.

General information: If you have any questions about Triveen-CF NAC, please talk with your doctor, pharmacist, or other health care provider. Triveen-CF NAC is to be used only by the patient for whom it is prescribed. Do not share it with other people. If your symptoms do not improve or if they become worse, check with your doctor. Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Triveen-CF NAC. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012 Database Edition 12.1.1.002 Copyright © 2012 Wolters Kluwer Health, Inc. More Triveen-CF NAC resources Triveen-CF NAC Use in Pregnancy & Breastfeeding Triveen-CF NAC Drug Interactions Triveen-CF NAC Support Group 4 Reviews for Triveen-CF NAC - Add your own review/rating Compare Triveen-CF NAC with other medications Dietary Supplementation Hyperhomocysteinemia
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Caladryl Clear


Generic Name: pramoxine topical (pra MOX een TOP i kal)
Brand Names: Anest Hemor, Blistex Pro Relief, Calaclear, Caladryl Clear, Callergy Clear, Curasore, Fleet Pain Relief Pad, Gold Bond Anti-Itch, Itch-X, PrameGel, Pramox, Prax, Proctofoam, Proctozone-P, Sarna Sensitive, Sarna Sensitive Eczema Itch Relief, Sarna Ultra, Soothe-It Plus Hemmorhoidal Pad, Summers Eve Anti-Itch, Tronolane

What is Caladryl Clear (pramoxine topical)?

Pramoxine is an anesthetic, or "numbing medicine." It works by interfering with pain signals sent from the nerves to the brain.

Pramoxine topical (for the skin) is used to treat pain or itching caused by insect bites, minor burns or scrapes, hemorrhoids, and minor skin rash, dryness, or itching. Pramoxine topical is also used to treat chapped lips, and pain or skin irritation caused by coming into contact with poison ivy, poison oak, or poison sumac.

Pramoxine topical may also be used for purposes not listed in this medication guide.

What is the most important information I should know about Caladryl Clear (pramoxine topical)?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Less serious side effects are more likely, and you may have none at all.

What should I discuss with my health care provider before using Caladryl Clear (pramoxine topical)? You should not use this medication if you are allergic to pramoxine.

Ask a doctor or pharmacist if it is safe for you to take this medicine if you are allergic to any drugs or any other numbing medicines.

FDA pregnancy category C. It is not known whether pramoxine topical will harm an unborn baby. Do not use this medication without medical advice if you are pregnant. It is not known whether pramoxine topical passes into breast milk or if it could harm a nursing baby. Do not use this medication without medical advice if you are breast-feeding a baby. How should I use Caladryl Clear (pramoxine topical)?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Pramoxine is usually applied to the affected area 3 to 5 times daily, depending on which form of this medication you use. Follow the label directions or your doctor's instructions about how much medication to use and how often.

Pramoxine hemorrhoid cream, lotion, foam, or medicated wipe may be used on the rectum after each bowel movement to treat hemorrhoid pain and itching.

Wash your hands before and after applying pramoxine topical. Wash the affected skin area with warm water and a mild soap. Rinse and dry the area thoroughly.

To use pramoxine on the skin, (spray, lotion, gel, or stick), apply just enough of the medication to cover the area to be treated.

To use the pramoxine medicated wipe to treat the hemorrhoid area, apply the medication by patting the wipe onto the rectal area. Avoid harsh rubbing. You may fold the wipe and leave it in place for up to 15 minutes. Each pramoxine medicated wipe is for one use only. Throw the wipe away after using.

Shake the pramoxine rectal foam before each use. Squirt only a small amount of the medicine onto a clean tissue and apply it to your rectum. Do not insert this medication or the medicated wipe into your rectum. Use pramoxine topical only on the outside of the area.

Stop using pramoxine and call your doctor if your symptoms do not improve after 7 days of treatment, or if your condition clears up and then comes back.

Store at room temperature away from moisture and heat. What happens if I miss a dose?

Since pramoxine topical is used on an as needed basis, you are not likely to miss a dose.

What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while using Caladryl Clear (pramoxine topical)? Avoid getting this medication in your eyes or nose. If this does happen, rinse with water. Do not use pramoxine topical on deep skin wounds, blistered skin, severe burns, or large skin areas. Seek medical attention for more severe skin irritation or injury.

Avoid using other medications on the areas you treat with pramoxine topical unless you doctor tells you to.

Caladryl Clear (pramoxine topical) side effects Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using pramoxine topical and call your doctor at once if you have a serious side effect such as:

any new redness or swelling where the medicine was applied; or

severe pain, burning, or stinging where the medicine is applied.

Less serious side effects are more likely, and you may have none at all.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Caladryl Clear (pramoxine topical)?

It is not likely that other drugs you take orally or inject will have an effect on topically applied pramoxine. But many drugs can interact with each other. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

More Caladryl Clear resources Caladryl Clear Side Effects (in more detail) Caladryl Clear Use in Pregnancy & Breastfeeding Caladryl Clear Support Group 0 Reviews for Caladryl Clear - Add your own review/rating Caladryl Clear MedFacts Consumer Leaflet (Wolters Kluwer) Itch-X Foam MedFacts Consumer Leaflet (Wolters Kluwer) PrameGel Gel MedFacts Consumer Leaflet (Wolters Kluwer) Pramoxine Hydrochloride Monograph (AHFS DI) Prax Lotion MedFacts Consumer Leaflet (Wolters Kluwer) Proctofoam Foam MedFacts Consumer Leaflet (Wolters Kluwer) Sarna Sensitive Lotion MedFacts Consumer Leaflet (Wolters Kluwer) Tronolane Cream MedFacts Consumer Leaflet (Wolters Kluwer) Compare Caladryl Clear with other medications Pruritus Where can I get more information? Your pharmacist can provide more information about pramoxine topical.

See also: Caladryl Clear side effects (in more detail)


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Vitamin E Deficiency Medications


Definition of Vitamin E Deficiency: A nutritional condition produced by a deficiency of vitamin e in the diet, characterised by posterior column and spinocerebellar tract abnormalities, areflexia, ophthalmoplegia, and disturbances of gait, proprioception, and vibration. In premature infants vitamin e deficiency is associated with haemolytic anaemia, thrombocytosis, oedema, intraventricular haemorrhage, and increasing risk of retrolental fibroplasia and bronchopulmonary dysplasia. An apparent inborn error of vitamin e metabolism, named familial isolated vitamin e deficiency, has recently been identified.

Drugs associated with Vitamin E Deficiency

The following drugs and medications are in some way related to, or used in the treatment of Vitamin E Deficiency. This service should be used as a supplement to, and NOT a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.


Drug List: Alpha-E Amino-Opti-E Aqua-Gem-E Aqua-E Aquasol-E Aquavite-E Centrum-Singles-Vitamin-E E-Pherol E-400-Clear E-600 E-Gems Nutr-E-Sol Vita-Plus-E-Natural
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Tobramycin/Dexamethasone Ointment


Pronunciation: toe-bra-MYE-sin/dex-a-METH-a-sone
Generic Name: Tobramycin/Dexamethasone
Brand Name: TobraDex
Tobramycin/Dexamethasone Ointment is used for:

Treating eye inflammation and bacterial infection.

Tobramycin/Dexamethasone Ointment is an antibiotic (tobramycin) and steroid (dexamethasone) combination eye ointment. The antibiotic works by killing bacteria and the steroid reduces redness, irritation, and swelling.

Do NOT use Tobramycin/Dexamethasone Ointment if: you are allergic to any ingredient in Tobramycin/Dexamethasone Ointment you have herpes simplex, vaccinia, varicella, or any other viral, mycobacterial, or fungal eye infection

Contact your doctor or health care provider right away if any of these apply to you.

Before using Tobramycin/Dexamethasone Ointment:

Some medical conditions may interact with Tobramycin/Dexamethasone Ointment. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, plan to become pregnant, or are breast-feeding if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement if you have allergies to medicines, foods, or other substances if you have thinning of the cornea or the white part of the eye if you have diabetes

Some MEDICINES MAY INTERACT with Tobramycin/Dexamethasone Ointment. Because little, if any, of Tobramycin/Dexamethasone Ointment is absorbed into the blood, the risk of it interacting with another medicine is low.

Ask your health care provider if Tobramycin/Dexamethasone Ointment may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Tobramycin/Dexamethasone Ointment:

Use Tobramycin/Dexamethasone Ointment as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Tobramycin/Dexamethasone Ointment is only for the eye. Do not get it in your nose or mouth. To use Tobramycin/Dexamethasone Ointment in the eye, first, wash your hands. Using your index finger, pull the lower eyelid away from your eye to form a pouch. Squeeze a thin strip of ointment into the pouch. After using Tobramycin/Dexamethasone Ointment, gently close your eyes for 1 to 2 minutes. Wash your hands to remove any medicine that may be on them. Wipe the applicator tip with a clean, dry tissue. To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including the eye. Keep the container tightly closed. Do not wear contact lenses while you are using Tobramycin/Dexamethasone Ointment. Take care of your contact lenses as directed by the manufacturer. Check with your doctor before you use them. Using Tobramycin/Dexamethasone Ointment at the same time each day will help you to remember to use it. To clear up your infection completely, use Tobramycin/Dexamethasone Ointment for the full course of treatment. Keep using it even if you feel better in a few days. If you miss a dose of Tobramycin/Dexamethasone Ointment, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Tobramycin/Dexamethasone Ointment.

Important safety information: Tobramycin/Dexamethasone Ointment may cause blurred vision. Use Tobramycin/Dexamethasone Ointment with caution. Do not drive or perform other possibly unsafe tasks if you cannot see clearly. If your symptoms do not improve within a few days or if they get worse, check with your doctor. Be sure to use Tobramycin/Dexamethasone Ointment for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future. Long-term or repeated use of Tobramycin/Dexamethasone Ointment may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this. Do not use Tobramycin/Dexamethasone Ointment for future eye problems unless directed by your doctor. Lab tests, including eye exams, may be performed while you use Tobramycin/Dexamethasone Ointment. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments. Tobramycin/Dexamethasone Ointment should not be used in CHILDREN younger than 2 years old; safety and effectiveness in these children have not been confirmed. PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Tobramycin/Dexamethasone Ointment while you are pregnant. It is not known if Tobramycin/Dexamethasone Ointment is found in breast milk. Do not breast-feed while taking Tobramycin/Dexamethasone Ointment. Possible side effects of Tobramycin/Dexamethasone Ointment:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Burning or stinging when you first put the medicine in your eye; delayed wound healing.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); changes in vision; itching and swelling of the eyelid; redness or swelling of the eye; second infection; severe eye pain; vision loss.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include flushing; increased tearing; lid itching; redness; swelling; spots or lesions on the surface of the cornea.

Proper storage of Tobramycin/Dexamethasone Ointment:

Store Tobramycin/Dexamethasone Ointment between 46 and 80 degrees F (8 and 27 degrees C). Store upright in the original container and away from heat, moisture, and light. Do not store in the bathroom. Keep Tobramycin/Dexamethasone Ointment out of the reach of children and away from pets.

General information: If you have any questions about Tobramycin/Dexamethasone Ointment, please talk with your doctor, pharmacist, or other health care provider. Tobramycin/Dexamethasone Ointment is to be used only by the patient for whom it is prescribed. Do not share it with other people. If your symptoms do not improve or if they become worse, check with your doctor. Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Tobramycin/Dexamethasone Ointment. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012 Database Edition 12.1.1.002 Copyright © 2012 Wolters Kluwer Health, Inc. More Tobramycin/Dexamethasone resources Tobramycin/Dexamethasone DosageTobramycin/Dexamethasone Use in Pregnancy & BreastfeedingTobramycin/Dexamethasone Drug InteractionsTobramycin/Dexamethasone Support Group3 Reviews for Tobramycin/Dexamethasone - Add your own review/rating Compare Tobramycin/Dexamethasone with other medications Conjunctivitis, BacterialKeratitisUveitis
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Maxitrol Drops


Pronunciation: DEX-a-METH-a-sone/NEE-oh-MYE-sin/POL-ee-MIX-in
Generic Name: Dexamethasone/Neomycin/Polymyxin B
Brand Name: Examples include Maxitrol and Poly-Dex
Maxitrol Drops are used for:

Treating eye infections and associated symptoms, including redness, irritation, and discomfort, caused by certain bacteria. It may also be used for other conditions as determined by your doctor.

Maxitrol Drops are a combination of 2 antibiotics and a corticosteroid (dexamethasone). The antibiotics work by slowing the growth of, or killing, sensitive bacteria on the eye. The corticosteroid reduces inflammation.

Do NOT use Maxitrol Drops if: you are allergic to any ingredient in Maxitrol Drops you have a fungal, viral (eg, herpes simplex, chickenpox, shingles), or mycobacterial infection of the eye

Contact your doctor or health care provider right away if any of these apply to you.

Before using Maxitrol Drops:

Some medical conditions may interact with Maxitrol Drops. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement if you have allergies to medicines, foods, or other substances if you have diabetes, glaucoma, or thinning of the cornea or white of the eye

Some MEDICINES MAY INTERACT with Maxitrol Drops. Because little, if any, of Maxitrol Drops are absorbed into the blood, the risk of it interacting with another medicine is low.

Ask your health care provider if Maxitrol Drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Maxitrol Drops:

Use Maxitrol Drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Maxitrol Drops are only for the eye. Do not get it in your nose or mouth. To prevent reinfection, wash your hands before and after using Maxitrol Drops. Shake well before each use. To use Maxitrol Drops in the eye, first, wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eyelid for 1 to 2 minutes. Do not blink. Remove excess medicine around your eye with a clean, dry tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them. To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including the eye. Keep the container tightly closed. Do not wear contact lenses while you are using Maxitrol Drops. Take care of your contact lenses as directed by the manufacturer. Check with your doctor before you use them. To clear up your infection completely, use Maxitrol Drops for the full course of treatment. Keep using it even if you feel better in a few days. If you miss a dose of Maxitrol Drops, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Maxitrol Drops.

Important safety information: Maxitrol Drops only works against bacteria; it does not treat viral infections (eg, the common cold). Be sure to use Maxitrol Drops for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future. Long-term or repeated use of Maxitrol Drops may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this. Long-term use of Maxitrol Drops may cause an increase in the pressure in your eyes. Do NOT take more than the recommended dose or use for longer than 10 days without checking with your doctor. Maxitrol Drops should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed. PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Maxitrol Drops while you are pregnant. It is not known if Maxitrol Drops are found in breast milk after topical use. If you are or will be breast-feeding while you use Maxitrol Drops, check with your doctor. Discuss any possible risks to your baby. Possible side effects of Maxitrol Drops:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Burning or stinging when you first put the medicine in your eye; dry, flaky skin; irritation; itching; redness; swelling.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); changes in vision; continued burning or itching; eye pain.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Maxitrol side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Maxitrol Drops:

Store Maxitrol Drops between 46 and 80 degrees F (8 and 27 degrees C). Store away from heat, moisture, and light. Keep the container tightly closed. Keep Maxitrol Drops out of the reach of children and away from pets.

General information: If you have any questions about Maxitrol Drops, please talk with your doctor, pharmacist, or other health care provider. Maxitrol Drops are to be used only by the patient for whom it is prescribed. Do not share it with other people. If your symptoms do not improve or if they become worse, check with your doctor. Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Maxitrol Drops. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012 Database Edition 12.1.1.002 Copyright © 2012 Wolters Kluwer Health, Inc. More Maxitrol resources Maxitrol Side Effects (in more detail) Maxitrol Use in Pregnancy & Breastfeeding Maxitrol Drug Interactions Maxitrol Support Group 0 Reviews for Maxitrol - Add your own review/rating Compare Maxitrol with other medications Blepharitis Conjunctivitis, Bacterial Keratitis Keratoconjunctivitis Uveitis
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Little Bottoms Daily Care Spray


Pronunciation: dye-METH-i-kone
Generic Name: Dimethicone
Brand Name: Little Bottoms Daily Care Spray
Little Bottoms Daily Care Spray is used for:

Temporarily protecting and relieving minor skin irritations (eg, diaper rash). It also helps to seal out wetness. It may also be used for other conditions as determined by the patient's doctor.

This product is a skin protectant. It works by relieving skin irritation and reducing redness.

Do NOT use Little Bottoms Daily Care Spray if: the patient is allergic to any ingredient in Little Bottoms Daily Care Spray

Contact your doctor or health care provider right away if this applies to the patient.

Before using Little Bottoms Daily Care Spray:

Tell the patient's health care provider if the patient has any medical conditions, especially if any of the following apply:

if the patient is pregnant, planning to become pregnant, or is breast-feeding if the patient is taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement if the patient has allergies to medicines, foods, or other substances

Some MEDICINES MAY INTERACT with Little Bottoms Daily Care Spray. However, no specific interactions with Little Bottoms Daily Care Spray are known at this time.

Ask the patient's health care provider if Little Bottoms Daily Care Spray may interact with other medicines that the patient takes. Check with the patient's health care provider before the patients starts, stops, or changes the dose of any medicine.

How to use Little Bottoms Daily Care Spray:

Use Little Bottoms Daily Care Spray as directed by the patient's doctor. Check the label on the medicine for exact dosing instructions.

Cleanse the diaper area and gently pat dry. Spray Little Bottoms Daily Care Spray onto the affected area as directed by the patient's doctor or on the package label. Wash your hands immediately after using Little Bottoms Daily Care Spray. Apply during each diaper change, especially at bedtime or any time that exposure to a wet diaper may be prolonged. If you miss a dose of Little Bottoms Daily Care Spray, use it as soon as you remember. Continue to use it as directed by the patient's doctor or on the package label.

Ask the patient's health care provider any questions you may have about how to use Little Bottoms Daily Care Spray.

Important safety information: Little Bottoms Daily Care Spray is for external use only. Do not get it in the eyes, nose, or mouth. If you get it in any of these areas, rinse right away with cool water. Do not use Little Bottoms Daily Care Spray on animal bites, deep wounds, infections, lacerations, or serious burns. If symptoms do not get better within 7 days, if they get worse, or if they clear up and then come back, check with the patient's doctor. Talk with the patient's doctor before you use any other medicines on the treated area. PREGNANCY and BREAST-FEEDING: If the patient becomes pregnant, contact her doctor. You will need to discuss the benefits and risks of using Little Bottoms Daily Care Spray while the patient is pregnant. It is not known if Little Bottoms Daily Care Spray is found in breast milk. If the patient is or will be breast-feeding while she uses Little Bottoms Daily Care Spray, check with her doctor. Discuss any possible risks to her baby. Possible side effects of Little Bottoms Daily Care Spray:

All medicines may cause side effects, but many people have no, or minor side effects. No COMMON side effects have been reported with Little Bottoms Daily Care Spray. Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); new or worsening skin irritation.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact the patient's health care provider. Call the patient's doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Little Bottoms Daily Care side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Little Bottoms Daily Care Spray may be harmful if swallowed.

Proper storage of Little Bottoms Daily Care Spray:

Store Little Bottoms Daily Care Spray at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Do not freeze. Keep Little Bottoms Daily Care Spray out of the reach of children and away from pets.

General information: If you have any questions about Little Bottoms Daily Care Spray, please talk with the patient's doctor, pharmacist, or other health care provider. Little Bottoms Daily Care Spray is to be used only by the patient for whom it is prescribed. Do not share it with other people. If the patient's symptoms do not improve or if they become worse, check with the patient's doctor. Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Little Bottoms Daily Care Spray. If you have questions about the medicine the patient is taking or would like more information, check with the patient's doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012 Database Edition 12.1.1.002 Copyright © 2012 Wolters Kluwer Health, Inc. More Little Bottoms Daily Care resources Little Bottoms Daily Care Side Effects (in more detail) Little Bottoms Daily Care Use in Pregnancy & Breastfeeding 0 Reviews for Little Bottoms Daily Care - Add your own review/rating Compare Little Bottoms Daily Care with other medications Dry Skin
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Curatoderm Ointment


1. Name Of The Medicinal Product

Curatoderm Ointment 4?g/g

2. Qualitative And Quantitative Composition

Tacalcitol monohydrate 4.17 ?g/g

(tacalcitol 4 ?g/g)

3. Pharmaceutical Form

Ointment

4. Clinical Particulars 4.1 Therapeutic Indications

Psoriasis vulgaris.

4.2 Posology And Method Of Administration

Adults and the Elderly: Apply sparingly, once daily to the affected areas, preferably at bedtime. The amount applied should not exceed l0g of ointment/day. Normally duration of treatment depends on the severity of the lesions and should be decided by the physician. There is clinical trial experience with continuous and intermittent treatment in adults up to twelve months.

Curatoderm Ointment can be used on all areas of the body (including face, hairline, scalp, axilla and other flexures).

When used on the scalp the ointment can be shampooed out the next morning.

Children: Not recommended. There is limited clinical experience in children.

4.3 Contraindications

Hypersensitivity to constituents; in patients with hypercalcaemia or other known disorders of calcium metabolism.

4.4 Special Warnings And Precautions For Use

At the doctor's discretion, in patients at risk of hypercalcaemia, or patients taking high Vitamin D preparations (in excess of 500 IU vitamin D) albumin corrected serum calcium levels should be closely monitored. Treatment should be stopped if hypercalcaemia occurs. Serum calcium levels should also be monitored in patients with renal impairment.

Care should be exercised in patients with generalised pustular or erythrodermic exfoliative psoriasis as the risk of hypercalcaemia may be enhanced.

When applying to the face avoid contact with the eyes. Patients should be advised to wash their hands after applying the ointment to avoid inadvertent transfer to other parts of the body.

4.5 Interaction With Other Medicinal Products And Other Forms Of Interaction

No interactions are likely in patients using multivitamin preparations with up to 500 IU vitamin D.

UVB radiation can be combined with Curatoderm Ointment. This approach increases the efficacy of the treatment and shortens the radiation period. UV radiation should be given in the morning and Curatoderm Ointment at bedtime. There has been limited experience of the concomitant use of Curatoderm Ointment with topical corticosteroids, urea, emollients, dithranol cream and PUVA.

4.6 Pregnancy And Lactation

The safety of this medicinal product for use in human pregnancy has not been established. Evaluation of experimental animal studies does not indicate direct or indirect harmful effects with respect to the development of the embryo or foetus, the course of gestation or peri- or postnatal development. Avoid use in pregnancy unless there are no safer alternatives. During lactation the breast area should not be treated. It is not known whether tacalcitol is excreted in human breast milk.

4.7 Effects On Ability To Drive And Use Machines

Not applicable.

4.8 Undesirable Effects

Local skin reactions (itching, erythema, burning, paraesthesia) have been reported. Other local reactions and in isolated cases contact dermatitis or a worsening of the skin condition may occur. In general, these local reactions are mild and transient.

4.9 Overdose

Overdosing by ingestion of an ointment is very unlikely. It cannot be excluded that topical application of excessive amounts may lead to hypercalcaemia. In this case Curatoderm treatment and other possible vitamin D or calcium supplement intakes must be stopped until serum calcium returns to normal.

5. Pharmacological Properties 5.1 Pharmacodynamic Properties

Pharmacotherapeutic group: D05A X02.

Tacalcitol is a vitamin D3 derivative, which inhibits keratinocyte hyper-proliferation and induces differentiation of these cells. The normalisation of these mechanisms is the basis for the efficacy in the treatment of psoriasis. In biopsies from patients treated with tacalcitol specific indicators for inflammation were improved. Tacalcitol binds to the keratinocyte vitamin D receptor to the same extent as natural active vitamin D3.

5.2 Pharmacokinetic Properties

Single or repeated application of tacalcitol ointment in humans results in less than 0.5% of the drug being systemically absorbed through psoriatic skin. Tacalcitol is completely bound to plasma proteins (vitamin D binding protein) The main metabolite is 1 ?, 24, 25 (OH)3 vitamin D3, a metabolite shared with the natural active vitamin, with 5-10 times less vitamin D activity. Tacalcitol and metabolites are excreted mainly in the faeces in rat and dog studies with excretion in urine in man. It cannot therefore be excluded that if there is sufficient systemic absorption accumulation may occur in patients with renal failure.

5.3 Preclinical Safety Data

Tacalcitol is effective in very low concentrations. The no-effect-level following cutaneous application over 12 months in rat studies amounted to only 4 ng/kg daily. Toxicity is focused to the classic vitamin effects of calciferols. Teratogenicity studies in mice and rats showed no teratogenic effects of tacalcitol. The results of mutagenicity studies (Ames test, chromosomal aberration test and micronucleus test), indicate no genotoxic potential.

6. Pharmaceutical Particulars 6.1 List Of Excipients

White petrolatum, liquid paraffin, diisopropyl adipate.

6.2 Incompatibilities

None known.

6.3 Shelf Life

36 months at up to 30°C. 6 months after first opening the tube.

6.4 Special Precautions For Storage

None.

6.5 Nature And Contents Of Container

Aluminium tubes with internal lacquer, membrane-sealed opening and plastic screw cap, containing 5g, 20g, 30g, 60g or 100g.

6.6 Special Precautions For Disposal And Other Handling

External use only.

7. Marketing Authorisation Holder

Almirall Hermal GmbH

Scholtzstrasse 3

D-21465,

Reinbek

Germany

8. Marketing Authorisation Number(S)

PL 33016/0012

9. Date Of First Authorisation/Renewal Of The Authorisation

13th July 2006

10. Date Of Revision Of The Text

31st July 2010


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methylcellulose


Generic Name: methylcellulose (METH il SEL yoo los)
Brand Names: Citrucel, Citrucel Clear Mix, Citrucel Food Pack, Citrucel Lax, Citrucel SF

What is methylcellulose?

Methylcellulose is a bulk-forming laxative. Methylcellulose absorbs liquid in the intestines and makes a bulky, softer stool which is easier to pass.

Methylcellulose helps relieve constipation and to maintain regularity.

Methylcellulose may also have uses other than those listed in this product guide.

What is the most important information I should know about methylcellulose? Do not use methylcellulose without first talking to your doctor if you have stomach (abdominal) pain, nausea, vomiting, or difficulty swallowing. Taking methylcellulose without enough liquid may cause it to swell in the throat and cause choking. If you experience chest pain, vomiting, difficulty swallowing, or difficulty breathing after taking methylcellulose, seek immediate medical attention. What should I discuss with my healthcare provider before taking methylcellulose? Do not take methylcellulose without first talking to your doctor if you have

stomach (abdominal) pain, nausea, or vomiting;

difficulty swallowing; or

intestinal obstruction or fecal impaction.

You may not be able to take methylcellulose or you may require special monitoring while taking methylcellulose if you have any of the conditions listed above.

Each level scoop of sugar-free methylcellulose powder contains 52 mg of phenylalanine. Individuals with phenylketonuria may need to monitor their intake of this additive.

Talk to your doctor before taking methylcellulose if you are pregnant or breast-feeding a baby. How should I take methylcellulose?

Take methylcellulose exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take methylcellulose capsules with a full glass (at least 8 ounces) of water or another liquid.

Mix methylcellulose powder with at least 8 ounces of water or another noncarbonated beverage. Mix briskly and drink promptly.

Taking methylcellulose without enough liquid may cause it to swell in the throat and cause choking.

If methylcellulose has produced no effect within one week or if rectal bleeding occurs, stop taking methylcellulose and contact your doctor. Do not take more methylcellulose than is recommended or for longer than one week except under the direction of your doctor.

If you experience chest pain, vomiting, difficulty swallowing, or difficulty breathing after taking methylcellulose, seek immediate medical attention. Store methylcellulose at room temperature away from moisture and heat. What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose.

What happens if I overdose? Seek emergency medical attention if an overdose is suspected.

Symptoms of a methylcellulose overdose are not known.

What should I avoid while taking methylcellulose?

There are no restrictions on foods, beverages, or activities during treatment with methylcellulose unless otherwise directed by your healthcare provider.

Methylcellulose side effects If you experience any of the following uncommon but serious side effects, stop taking methylcellulose and seek medical treatment or contact your doctor immediately:

an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);

chest pain;

difficulty swallowing;

rectal bleeding; or

severe abdominal pain, nausea or vomiting.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Methylcellulose Dosing Information

Usual Adult Dose for Constipation:

2 tablets (1000 mg) orally with 8 oz of liquid up to 6 times a day, or 1 heaping tablespoonful (19 g) of powder dissolved in 8 oz of cold water orally up to 3 times a day, or 1 heaping tablespoonful (10.2 g) of sugar-free powder dissolved in 8 oz of cold water orally up to 3 times a day.

Usual Pediatric Dose for Constipation:

6 to 12 years:
1 tablet (500 mg) orally with 8 oz of liquid up to 6 times a day, or one-half tablespoonful (9.5 g) of powder dissolved in 8 oz of cold water orally once a day, or one-half tablespoonful (5.1 g) of sugar-free powder dissolved in 8 oz of cold water orally once a day. The mixture should be administered promptly, and drinking another glass of water is highly recommended.
>12 years:
oral tablet:
2 tablets (1000 mg) orally with 8 oz of liquid up to 6 times a day, or 1 heaping tablespoonful (19 g) of powder dissolved in 8 oz of cold water orally up to 3 times a day, or 1 heaping tablespoonful (10.2 g) of sugar-free powder dissolved in 8 oz of cold water orally up to 3 times a day.

What other drugs will affect methylcellulose?

Methylcellulose can interact with other medications. Before taking methylcellulose, talk to your doctor if you are taking any prescription or over-the-counter medicines. You may not be able to take methylcellulose, or you may require a dosage adjustment or special monitoring if you are taking any other medicines.

More methylcellulose resources Methylcellulose Side Effects (in more detail) Methylcellulose Use in Pregnancy & Breastfeeding Methylcellulose Drug Interactions Methylcellulose Support Group 2 Reviews for Methylcellulose - Add your own review/rating Methylcellulose MedFacts Consumer Leaflet (Wolters Kluwer) Citrucel Prescribing Information (FDA) Compare methylcellulose with other medications Constipation Where can I get more information? Your pharmacist has more information about methylcellulose written for health professionals that you may read.

See also: methylcellulose side effects (in more detail)


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HYDREX CLEAR CHLORHEXIDINE GLUCONATE 0.5% W / V IN 70% V / V DEB.


1. Name Of The Medicinal Product

HYDREX®, CLEAR CHLORHEXIDINE GLUCONATE 0.5% W/V IN 70% V/V DEB.

2. Qualitative And Quantitative Composition

Chlorhexidine Gluconate Solution 20% BP (Ph Eur) – 2.5% v/v

3. Pharmaceutical Form

Liquid

4. Clinical Particulars 4.1 Therapeutic Indications

This product is for pre-operative skin disinfection prior to minor surgical procedures

4.2 Posology And Method Of Administration

This product is applied topically.

4.3 Contraindications

i) Do not use in patients who are hypersensitive to chlorhexidine.

ii) Do not use in contact with eyes, brain, meninges, middle ear or external ear with a perforated tympanic membrane.

iii) Do not inject.

iv) Do not use in body cavities.

v) When use is to be followed by diathermy do not allow pooling of the fluid to occur and ensure that the skin and surrounding drapes are dry.

4.4 Special Warnings And Precautions For Use

i) Precautions:- irritant skin reaction and generated allergic reactions to chlorhexidine have been reported.

ii) Accidental ingestion:- chlorhexidine is poorly absorbed orally. Treat with gastric lavage using milk, egg white, gelatin or mild soap. Employ supportive measures as appropriate.

iii) Accidental intravenous infusion - blood transfusion may be necessary to counteract haemolysis.

4.5 Interaction With Other Medicinal Products And Other Forms Of Interaction

None stated

4.6 Pregnancy And Lactation

None stated

4.7 Effects On Ability To Drive And Use Machines

None stated

4.8 Undesirable Effects

None stated

4.9 Overdose

None stated

5. Pharmacological Properties 5.1 Pharmacodynamic Properties

None stated

5.2 Pharmacokinetic Properties

None stated

5.3 Preclinical Safety Data

None stated

6. Pharmaceutical Particulars 6.1 List Of Excipients

Denatured Ethanol B 96%

Purified Water BP

6.2 Incompatibilities

Not applicable

6.3 Shelf Life

3 years

6.4 Special Precautions For Storage

Do not store above 25°C. Store in the original package.

6.5 Nature And Contents Of Container

Hydrex, Clear Chlorhexidine is packaged in HDPE containers in the following sizes 50ml, 200ml, 500ml, 600ml, 1000ml and 2000ml.

6.6 Special Precautions For Disposal And Other Handling

Not applicable

7. Marketing Authorisation Holder

Ecolab Ltd, Lotherton Way, Garforth, Leeds, LS25 2JY.

8. Marketing Authorisation Number(S)

PL 04509/0017

9. Date Of First Authorisation/Renewal Of The Authorisation

1 March 2003

10. Date Of Revision Of The Text

August 2006 / November 2008


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chondroitin, glucosamine, and methylsulfonylmethane


Generic Name: chondroitin, glucosamine, and methylsulfonylmethane (kon DROI tin, gloo KOSE a meen, and METH il sul FON il METH ane)
Brand names: Glucosamine & Chondroitin with MSM, Glucosamine Chondroitin MSM Complex, Osteo Bi-Flex Advanced, Osteo Bi-Flex Plus MSM, Glucosamine & Chondroitin with MSM

What is chondroitin, glucosamine, and methylsulfonylmethane?

Chondroitin is a naturally occurring substance formed of sugar chains. Chondroitin is believed to help the body maintain fluid and flexibility in the joints.

Glucosamine is a naturally occurring substance that is believed to help develop and renew cartilage (the hard connective tissue mainly located on bones near joints in the body), and keep it lubricated for better joint movement and flexibility.

Methylsulfonylmethane is a naturally occurring form of sulfur that helps support muscles and tendons in the body.

The combination of chondroitin, glucosamine, and methylsulfonylmethane is used to aid in maintaining healthy joints. It is also used as a nutritional supplement in people with osteoarthritis or other inflammatory joint disorders.

Not all uses for chondroitin, glucosamine, and methylsulfonylmethane have been approved by the FDA. Chondroitin, glucosamine, and methylsulfonylmethane should not be used in place of medication prescribed for you by your doctor.

Chondroitin, glucosamine, and methylsulfonylmethane is often sold as an herbal supplement. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination.

Chondroitin, glucosamine, and methylsulfonylmethane may also be used for purposes not listed in this product guide.

What is the most important information I should know about chondroitin, glucosamine, and methylsulfonylmethane? Not all uses for this product have been approved by the FDA. Chondroitin, glucosamine, and methylsulfonylmethane should not be used in place of medication prescribed for you by your doctor.

Chondroitin, glucosamine, and methylsulfonylmethane is often sold as an herbal supplement. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination.

Before using this product, talk to your doctor, pharmacist, herbalist, or other healthcare provider. You may not be able to use chondroitin, glucosamine, and methylsulfonylmethane if you have diabetes, a bleeding or blood clotting disorder such as hemophilia, if you have allergies to certain drugs, if you are overweight, or if you are on a low-salt diet.

Do not take chondroitin, glucosamine, and methylsulfonylmethane without the medical advice if you are using insulin, or a blood thinner such as warfarin (Coumadin, Jantoven). Avoid taking chitosan (usually marketed as a weight-loss product) while you are taking chondroitin, glucosamine, and methylsulfonylmethane. Chitosan can make it harder for your body to absorb chondroitin. What should I discuss with my healthcare provider before taking chondroitin, glucosamine, and methylsulfonylmethane? You should not use this product if you are allergic to it.

Ask a doctor, pharmacist, herbalist, or other healthcare provider if it is safe for you to use this product if you have:

diabetes;

a bleeding or blood clotting disorder such as hemophilia;

if you have allergies to certain drugs;

if you are overweight; or

if you are on a low-salt diet.

It is not known whether chondroitin, glucosamine, and methylsulfonylmethane will harm an unborn baby. Tell your healthcare provider if you are pregnant or plan to become pregnant while using this product. It is not known whether chondroitin, glucosamine, and methylsulfonylmethane passes into breast milk or if it could harm a nursing baby. Do not use this product without telling your healthcare provider if you are breast-feeding a baby. How should I take chondroitin, glucosamine, and methylsulfonylmethane?

When considering the use of herbal supplements, seek the advice of your doctor. You may also consider consulting a practitioner who is trained in the use of herbal/health supplements.

If you choose to use chondroitin, glucosamine, and methylsulfonylmethane, use it as directed on the package or as directed by your doctor, pharmacist, or other healthcare provider. Do not use more of this product than is recommended on the label.

It may take up several weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve after a few weeks of treatment.

Glucosamine may increase the glucose (sugar) levels in your blood. If you have diabetes, you may need to check your blood sugar more often while taking this medication. You may also need to adjust your insulin dosage. Do not change your dose or medication schedule without advice from your doctor.

Chondroitin, glucosamine, and methylsulfonylmethane may be only part of a complete program of treatment that also includes diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely.

Store at room temperature away from moisture, heat, and light. What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while taking chondroitin, glucosamine, and methylsulfonylmethane? Avoid taking chitosan (usually marketed as a weight-loss product) while you are taking chondroitin, glucosamine, and methylsulfonylmethane. Chitosan can make it harder for your body to absorb chondroitin. Chondroitin, glucosamine, and methylsulfonylmethane side effects Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Less serious side effects may include:

mild nausea, upset stomach;

heartburn; or

diarrhea.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect chondroitin, glucosamine, and methylsulfonylmethane?

Tell your doctor about all other medicines you use, especially:

insulin; or

a blood thinner such as warfarin (Coumadin, Jantoven).

This list is not complete and other drugs may interact with chondroitin, glucosamine, and methylsulfonylmethane. Tell your healthcare provider about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More chondroitin, glucosamine, and methylsulfonylmethane resources Chondroitin, glucosamine, and methylsulfonylmethane Drug Interactions Chondroitin, glucosamine, and methylsulfonylmethane Support Group 1 Review for Chondroitin, glucosamine, and methylsulfonylmethane - Add your own review/rating Compare chondroitin, glucosamine, and methylsulfonylmethane with other medications Dietary Supplementation Osteoarthritis Where can I get more information? Consult with a licensed healthcare professional before using any herbal/health supplement. Whether you are treated by a medical doctor or a practitioner trained in the use of natural medicines/supplements, make sure all your healthcare providers know about all of your medical conditions and treatments.
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TobraDex ST Drops


Pronunciation: TOE-bra-MYE-sin/DEX-a-METH-a-sone
Generic Name: Tobramycin/Dexamethasone
Brand Name: TobraDex ST
TobraDex ST Drops are used for:

Treating certain types of eye inflammation where a bacterial infection exists or may develop.

TobraDex ST Drops are an antibiotic (tobramycin) and a corticosteroid (dexamethasone) combination. The antibiotic works by preventing the growth of, or killing, sensitive bacteria in the eye. The corticosteroid works by reducing inflammatory reactions.

Do NOT use TobraDex ST Drops if: you are allergic to any ingredient in TobraDex ST Drops you have a mycobacterial, fungal, or viral (eg, herpes simplex, vaccinia, chickenpox) eye infection

Contact your doctor or health care provider right away if any of these apply to you.

Before using TobraDex ST Drops:

Some medical conditions may interact with TobraDex ST Drops. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, plan to become pregnant, or are breast-feeding if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement if you have allergies to medicines, especially to other aminoglycosides (eg, gentamicin); foods; or other substances if you have thinning of the cornea (the surface of the eye), or oozing from the eye if you have diabetes, glaucoma or increased eye pressure, or have recently had cataract surgery if you have a history of viral eye infections (eg, herpes simplex) if you are using another form of aminoglycoside antibiotic (eg, intravenous)

Some MEDICINES MAY INTERACT with TobraDex ST Drops. Because little, if any, of TobraDex ST Drops are absorbed into the blood, the risk of interacting with another medicine is low.

Ask your health care provider if TobraDex ST Drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use TobraDex ST Drops:

Use TobraDex ST Drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.

TobraDex ST Drops are only for the eye. Do not get it in your nose or mouth. Do not inject it into the eye. Shake well before each use. To use TobraDex ST Drops in the eye, first wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eyelid for 1 to 2 minutes. Do not blink. Remove excess medicine around your eye with a clean, dry tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them. To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including the eye. Keep the container tightly closed. Do not wear contact lenses while you are using TobraDex ST Drops. Take care of your contact lenses as directed by the manufacturer. Check with your doctor before you use them. Using TobraDex ST Drops at the same time each day will help you to remember to use it. To clear up your infection completely, use TobraDex ST Drops for the full course of treatment. Keep using it even if you feel better in a few days. If you miss a dose of TobraDex ST Drops, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use TobraDex ST Drops.

Important safety information: TobraDex ST Drops may cause blurred vision. Use TobraDex ST Drops with caution. Do not drive or perform other possibly unsafe tasks if you cannot see clearly. If your symptoms do not improve within 2 days or if they get worse, check with your doctor. Check with your doctor if you have an eye wound or irritation that does not heal. Prolonged use of TobraDex ST Drops (eg, 10 days or longer) may increase the risk of glaucoma. Your doctor may monitor the pressure in your eye(s) while you use TobraDex ST Drops. Discuss any questions or concerns with your doctor. Be sure to use TobraDex ST Drops for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future. Long-term or repeated use of TobraDex ST Drops may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this. Do not use TobraDex ST Drops for future eye problems unless directed by your doctor. TobraDex ST Drops should be used with extreme caution in CHILDREN younger than 2 years old; safety and effectiveness in these children have not been confirmed. PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using TobraDex ST Drops while you are pregnant. It is not known if TobraDex ST Drops are found in breast milk after topical use. If you are or will be breast-feeding while you use TobraDex ST Drops, check with your doctor. Discuss any possible risks to your baby. Possible side effects of TobraDex ST Drops:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Burning or stinging when you first put the medicine in your eye.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); changes in vision; itching or swelling of the eyelid; new or worsening eye pain, redness, swelling, or irritation; vision loss.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: TobraDex ST side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include increased tearing; lid itching; redness or swelling of the eye.

Proper storage of TobraDex ST Drops:

Store TobraDex ST Drops between 36 and 77 degrees F (2 and 25 degrees C). Store upright in the original container, tightly closed, and away from heat, moisture, and light. Do not store in the bathroom. Keep TobraDex ST Drops out of the reach of children and away from pets.

General information: If you have any questions about TobraDex ST Drops, please talk with your doctor, pharmacist, or other health care provider. TobraDex ST Drops are to be used only by the patient for whom it is prescribed. Do not share it with other people. If your symptoms do not improve or if they become worse, check with your doctor. Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about TobraDex ST Drops. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012 Database Edition 12.1.1.002 Copyright © 2012 Wolters Kluwer Health, Inc. More TobraDex ST resources TobraDex ST Side Effects (in more detail) TobraDex ST Use in Pregnancy & Breastfeeding TobraDex ST Drug Interactions TobraDex ST Support Group 0 Reviews for TobraDex ST - Add your own review/rating Compare TobraDex ST with other medications Conjunctivitis, Bacterial Keratitis Uveitis
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TobraDex Drops


Pronunciation: TOE-bra-MYE-sin/DEX-a-METH-a-sone
Generic Name: Tobramycin/Dexamethasone
Brand Name: TobraDex
TobraDex Drops are used for:

Treating certain types of eye inflammation where a bacterial infection exists or may develop.

TobraDex Drops are an antibiotic (tobramycin) and a corticosteroid (dexamethasone) combination. The antibiotic works by preventing the growth of, or killing, sensitive bacteria in the eye. The corticosteroid works by reducing inflammatory reactions.

Do NOT use TobraDex Drops if: you are allergic to any ingredient in TobraDex Drops you have a mycobacterial, fungal, or viral (eg, herpes simplex, vaccinia, chickenpox) eye infection

Contact your doctor or health care provider right away if any of these apply to you.

Before using TobraDex Drops:

Some medical conditions may interact with TobraDex Drops. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, plan to become pregnant, or are breast-feeding if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement if you have allergies to medicines, especially to other aminoglycosides (eg, gentamicin); foods; or other substances if you have thinning of the cornea (the surface of the eye), or oozing from the eye if you have diabetes, glaucoma or increased eye pressure, or have recently had cataract surgery if you have a history of viral eye infections (eg, herpes simplex) if you are using another form of aminoglycoside antibiotics (eg, intravenous)

Some MEDICINES MAY INTERACT with TobraDex Drops. Because little, if any, of TobraDex Drops are absorbed into the blood, the risk of interacting with another medicine is low.

Ask your health care provider if TobraDex Drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use TobraDex Drops:

Use TobraDex Drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.

TobraDex Drops are only for the eye. Do not get it in your nose or mouth. Do not inject it into the eye. Shake well before each use. To use TobraDex Drops in the eye, first wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eyelid for 1 to 2 minutes. Do not blink. Remove excess medicine around your eye with a clean, dry tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them. To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including the eye. Keep the container tightly closed. Do not wear contact lenses while you are using TobraDex Drops. Take care of your contact lenses as directed by the manufacturer. Check with your doctor before you use them. Using TobraDex Drops at the same time each day will help you to remember to use it. To clear up your infection completely, use TobraDex Drops for the full course of treatment. Keep using it even if you feel better in a few days. If you miss a dose of TobraDex Drops, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use TobraDex Drops.

Important safety information: TobraDex Drops may cause blurred vision. Use TobraDex Drops with caution. Do not drive or perform other possibly unsafe tasks if you cannot see clearly. If your symptoms do not improve within a few days or if they get worse, check with your doctor. Check with your doctor if you have an eye wound or irritation that does not heal. Prolonged use of TobraDex Drops (eg, 10 days or longer) may increase the risk of glaucoma. Your doctor may monitor the pressure in your eye(s) while you use TobraDex Drops. Discuss any questions or concerns with your doctor. Be sure to use TobraDex Drops for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future. Long-term or repeated use of TobraDex Drops may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this. Do not use TobraDex Drops for future eye problems unless directed by your doctor. TobraDex Drops should be used with extreme caution in CHILDREN younger than 2 years old; safety and effectiveness in these children have not been confirmed. PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using TobraDex Drops while you are pregnant. It is not known if TobraDex Drops are found in breast milk after topical use. If you are or will be breast-feeding while you use TobraDex Drops, check with your doctor. Discuss any possible risks to your baby. Possible side effects of TobraDex Drops:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Burning or stinging when you first put the medicine in your eye.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); changes in vision; itching or swelling of the eyelid; new or worsening eye pain, redness, swelling, or irritation; vision loss.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: TobraDex side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include increased tearing; lid itching; redness or swelling of the eye.

Proper storage of TobraDex Drops:

Store TobraDex Drops between 46 and to 80 degrees F (8 and 27 degrees C). Store upright in the original container, tightly closed, and away from heat, moisture, and light. Do not store in the bathroom. Keep TobraDex Drops out of the reach of children and away from pets.

General information: If you have any questions about TobraDex Drops, please talk with your doctor, pharmacist, or other health care provider. TobraDex Drops are to be used only by the patient for whom it is prescribed. Do not share it with other people. If your symptoms do not improve or if they become worse, check with your doctor. Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about TobraDex Drops. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012 Database Edition 12.1.1.002 Copyright © 2012 Wolters Kluwer Health, Inc. More TobraDex resources TobraDex Side Effects (in more detail) TobraDex Use in Pregnancy & Breastfeeding TobraDex Drug Interactions TobraDex Support Group 3 Reviews for TobraDex - Add your own review/rating Compare TobraDex with other medications Conjunctivitis, Bacterial Keratitis Uveitis
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Tobramycin/Dexamethasone Drops


Pronunciation: TOE-bra-MYE-sin/DEX-a-METH-a-sone
Generic Name: Tobramycin/Dexamethasone
Brand Name: TobraDex ST
Tobramycin/Dexamethasone Drops are used for:

Treating certain types of eye inflammation where a bacterial infection exists or may develop.

Tobramycin/Dexamethasone Drops are an antibiotic (tobramycin) and a corticosteroid (dexamethasone) combination. The antibiotic works by preventing the growth of, or killing, sensitive bacteria in the eye. The corticosteroid works by reducing inflammatory reactions.

Do NOT use Tobramycin/Dexamethasone Drops if: you are allergic to any ingredient in Tobramycin/Dexamethasone Drops you have a mycobacterial, fungal, or viral (eg, herpes simplex, vaccinia, chickenpox) eye infection

Contact your doctor or health care provider right away if any of these apply to you.

Before using Tobramycin/Dexamethasone Drops:

Some medical conditions may interact with Tobramycin/Dexamethasone Drops. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, plan to become pregnant, or are breast-feeding if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement if you have allergies to medicines, especially to other aminoglycosides (eg, gentamicin); foods; or other substances if you have thinning of the cornea (the surface of the eye), or oozing from the eye if you have diabetes, glaucoma or increased eye pressure, or have recently had cataract surgery if you have a history of viral eye infections (eg, herpes simplex) if you are using another form of aminoglycoside antibiotic (eg, intravenous)

Some MEDICINES MAY INTERACT with Tobramycin/Dexamethasone Drops. Because little, if any, of Tobramycin/Dexamethasone Drops are absorbed into the blood, the risk of interacting with another medicine is low.

Ask your health care provider if Tobramycin/Dexamethasone Drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Tobramycin/Dexamethasone Drops:

Use Tobramycin/Dexamethasone Drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Tobramycin/Dexamethasone Drops are only for the eye. Do not get it in your nose or mouth. Do not inject it into the eye. Shake well before each use. To use Tobramycin/Dexamethasone Drops in the eye, first wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eyelid for 1 to 2 minutes. Do not blink. Remove excess medicine around your eye with a clean, dry tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them. To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including the eye. Keep the container tightly closed. Do not wear contact lenses while you are using Tobramycin/Dexamethasone Drops. Take care of your contact lenses as directed by the manufacturer. Check with your doctor before you use them. Using Tobramycin/Dexamethasone Drops at the same time each day will help you to remember to use it. To clear up your infection completely, use Tobramycin/Dexamethasone Drops for the full course of treatment. Keep using it even if you feel better in a few days. If you miss a dose of Tobramycin/Dexamethasone Drops, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Tobramycin/Dexamethasone Drops.

Important safety information: Tobramycin/Dexamethasone Drops may cause blurred vision. Use Tobramycin/Dexamethasone Drops with caution. Do not drive or perform other possibly unsafe tasks if you cannot see clearly. If your symptoms do not improve within 2 days or if they get worse, check with your doctor. Check with your doctor if you have an eye wound or irritation that does not heal. Prolonged use of Tobramycin/Dexamethasone Drops (eg, 10 days or longer) may increase the risk of glaucoma. Your doctor may monitor the pressure in your eye(s) while you use Tobramycin/Dexamethasone Drops. Discuss any questions or concerns with your doctor. Be sure to use Tobramycin/Dexamethasone Drops for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future. Long-term or repeated use of Tobramycin/Dexamethasone Drops may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this. Do not use Tobramycin/Dexamethasone Drops for future eye problems unless directed by your doctor. Tobramycin/Dexamethasone Drops should be used with extreme caution in CHILDREN younger than 2 years old; safety and effectiveness in these children have not been confirmed. PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Tobramycin/Dexamethasone Drops while you are pregnant. It is not known if Tobramycin/Dexamethasone Drops are found in breast milk after topical use. If you are or will be breast-feeding while you use Tobramycin/Dexamethasone Drops, check with your doctor. Discuss any possible risks to your baby. Possible side effects of Tobramycin/Dexamethasone Drops:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Burning or stinging when you first put the medicine in your eye.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); changes in vision; itching or swelling of the eyelid; new or worsening eye pain, redness, swelling, or irritation; vision loss.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include increased tearing; lid itching; redness or swelling of the eye.

Proper storage of Tobramycin/Dexamethasone Drops:

Store Tobramycin/Dexamethasone Drops between 36 and 77 degrees F (2 and 25 degrees C). Store upright in the original container, tightly closed, and away from heat, moisture, and light. Do not store in the bathroom. Keep Tobramycin/Dexamethasone Drops out of the reach of children and away from pets.

General information: If you have any questions about Tobramycin/Dexamethasone Drops, please talk with your doctor, pharmacist, or other health care provider. Tobramycin/Dexamethasone Drops are to be used only by the patient for whom it is prescribed. Do not share it with other people. If your symptoms do not improve or if they become worse, check with your doctor. Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Tobramycin/Dexamethasone Drops. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012 Database Edition 12.1.1.002 Copyright © 2012 Wolters Kluwer Health, Inc. More Tobramycin/Dexamethasone resources Tobramycin/Dexamethasone Use in Pregnancy & Breastfeeding Tobramycin/Dexamethasone Drug Interactions Tobramycin/Dexamethasone Support Group 3 Reviews for Tobramycin/Dexamethasone - Add your own review/rating Compare Tobramycin/Dexamethasone with other medications Conjunctivitis, Bacterial Keratitis Uveitis
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Polytrim Solution


Pronunciation: POL-ee-MIX-in/trye-METH-oh-prim
Generic Name: Polymyxin B Sulfate/Trimethoprim
Brand Name: Polytrim
Polytrim Solution is used for:

Treating eye infections caused by certain bacteria.

Polytrim Solution is an antibiotic combination. It works by killing the bacteria.

Do NOT use Polytrim Solution if: you are allergic to any ingredient in Polytrim Solution

Contact your doctor or health care provider right away if any of these apply to you.

Before using Polytrim Solution:

Some medical conditions may interact with Polytrim Solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement if you have allergies to medicines, foods, or other substances if you have the blood disease porphyria

Some MEDICINES MAY INTERACT with Polytrim Solution. Because little, if any, of Polytrim Solution is absorbed into the blood, the risk of it interacting with another medicine is low.

Ask your health care provider if Polytrim Solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Polytrim Solution:

Use Polytrim Solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.

To use Polytrim Solution in the eye, first, wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eyelid for 1 to 2 minutes. Do not blink. Remove excess medicine around your eye with a clean, dry tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them. To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including the eye. Keep the container tightly closed. Do not wear contact lenses while you are using Polytrim Solution. Take care of your contact lenses as directed by the manufacturer. Check with your doctor before you use them. If you miss a dose of Polytrim Solution, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Polytrim Solution.

Important safety information: Be sure to use Polytrim Solution for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future. Long-term or repeated use of Polytrim Solution may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this. If redness, irritation, swelling, or pain continues or worsens, check with your doctor. Polytrim Solution should be used with extreme caution in CHILDREN younger than 2 months old; safety and effectiveness in these children have not been confirmed. PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Polytrim Solution while you are pregnant. It is not known if Polytrim Solution is found in breast milk. If you are or will be breast-feeding while you use Polytrim Solution, check with your doctor. Discuss any possible risks to your baby. Possible side effects of Polytrim Solution:

All medicines may cause side effects, but many people have no, or minor, side effects. No COMMON side effects have been reported with this product. Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); eyelid swelling; increased or persistent redness, irritation, swelling, pain, or tearing of the eye.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Polytrim side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Polytrim Solution:

Store Polytrim Solution between 59 and 77 degrees F (15 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Polytrim Solution out of the reach of children and away from pets.

General information: If you have any questions about Polytrim Solution, please talk with your doctor, pharmacist, or other health care provider. Polytrim Solution is to be used only by the patient for whom it is prescribed. Do not share it with other people. If your symptoms do not improve or if they become worse, check with your doctor. Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Polytrim Solution. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012 Database Edition 12.1.1.002 Copyright © 2012 Wolters Kluwer Health, Inc. More Polytrim resources Polytrim Side Effects (in more detail) Polytrim Use in Pregnancy & Breastfeeding Polytrim Support Group 0 Reviews for Polytrim - Add your own review/rating Compare Polytrim with other medications Blepharoconjunctivitis Conjunctivitis, Bacterial
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Gastrografin


Due to regulatory changes, the content of the following Patient Information Leaflet may vary from the one found in your medicine pack. Please compare the 'Leaflet prepared/revised date' towards the end of the leaflet to establish if there have been any changes.
If you have any doubts or queries about your medication, please contact your doctor or pharmacist.

GASTROGRAFIN SOLUTION

Sodium amidotrizoate and meglumine amidotrizoate

Read all of this leaflet carefully before you are given this medicine. Keep this leaflet. You may need to read it again. If you have any further questions, ask the doctor giving you Gastrografin (the radiologist) or the X-ray department staff If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or the X-ray department staff/radiologist. In this leaflet: 1. What Gastrografin is and what it is used for 2. Before you are given Gastrografin 3. How you will be given Gastrografin 4. Possible side effects 5. How to store Gastrografin 6. Further information What Gastrografin is and what it is used for

Gastrografin is a contrast medium (a dye) which contains iodine. It is used to clearly show on X-rays the area of your body that your doctor wants to investigate. This will be your gullet (oesophagus), stomach or intestines (gastrointestinal tract). It may also be used to treat an intestinal obstruction in newborn babies (meconium ileus).

X-rays, like radio waves, can pass through objects and can be focused to make a picture. When you have an X-ray, the beam of rays goes through your body where it is absorbed to differing degrees by different tissues such as bones, muscles and organs. When the rays come out on the other side they make a pattern of light and shade on a film. Gastrografin helps to make this pattern clearer. The film is then examined by a specialist who will make a diagnosis.

This medicine is for diagnostic use only.

Before you are given Gastrografin Do not use Gastrografin if: you are, or suspect you are, allergic (hypersensitive) to iodine or iodine-containing contrast media or any of the other ingredients of Gastrografin (see Section 6: Further Information) you have a condition caused by too much thyroid hormone (manifest hyperthyroidism). Take special care with Gastrografin: You must tell the X-ray department staff if you have any of the following: any type of thyroid disease (e.g. hyperthyroidism). a history of allergy or a tendency to develop hypersensitivity reactions (for example if you have hay fever, asthma or eczema) heart or blood circulation problems, because in the rare event that you have an allergic reaction, it is more likely to be serious or fatal.

Gastrografin may affect the way the thyroid gland works for several weeks after being given it. If you are going to have an iodine test for thyroid disease, tell your doctor or the laboratory staff if you have received Gastrografin recently.

Taking or using other medicines

Please tell the radiologist or X-ray department staff if you are taking or have recently taken any other medicines, including medicines obtained without prescription. This is particularly important for:

beta-blockers (drugs used to treat heart or blood pressure), because they can make allergic reactions worse if you have been treated with a drug called interleukin, because there is a higher chance of getting delayed reactions (e.g. fever flu-like symptoms, joint pain and pruritus (itching)).

Ask the X-ray department staff if you are not sure.

Using with food and drink

Before the examination the X-ray department staff should make sure that you have had enough to drink and that any imbalances in your body water and body salts are corrected.

Pregnancy and breast-feeding

Tell the X-ray department staff if you are pregnant or breast-feeding or think you may be pregnant.

How you will be given Gastrografin

The X-ray department staff will explain how everything works and what position you should lie in on the X-ray table.

The dose of Gastrografin and how it will be given will depend on the type of investigation. The dose range is usually from 2ml to 125 ml Gastrografin. This may be diluted depending on the type of investigation.

Gastrografin is either drunk as a solution or given as an enema, a liquid that is forced by low pressure into the anus. It must not be given by injection into the blood vessels.

If you receive more Gastrografin than you should

Overdosing is unlikely. If it does happen the radiologist will treat any symptoms that follow.

Gastrografin Side Effects

Like all medicines, Gastrografin can cause side effects, although not everybody gets them.

If you notice:

itching of the skin, rash, wheals on the skin (urticaria) difficulty breathing, gagging, feeling of suffocation swelling of the face, neck or body itchy or watery eyes, tickling in the throat or nose, hoarseness, coughing or sneezing headache, dizziness, feeling faint feeling particularly hot or cold, sweating paleness or reddening of the skin chest pain, cramp, tremor feeling sick

Tell the radiologist or X-ray staff immediately as these may be the first signs of allergic reaction or shock. Your investigation will need to be stopped, and you may need further treatment.

Apart from the symptoms listed above the other side effects that you might experience are:

feeling sick or being sick diarrhoea anaphylactic shock (a very severe allergic reaction) allergic-type skin reactions including itching, redness, wheals on the skin overactive thyroid gland (hyperthyroidism) disorder of your body water and body salts balance fainting, dizziness, headache fast heart beat, sudden stopping of the heart (cardiac arrest), low blood pressure, shock difficulty breathing, swelling or fluid in the lungs. If Gastrografin gets into your lungs by accident it may cause fluid to collect in your lungs abdominal pain, holes in the gut wall (intestinal perforation) blistering inside the nose or mouth severe skin disease (red, blistered, bleeding, painful skin, which may affect the lips, eyes, mouth, nose and genitals too) rash, redness of the skin swelling of the face fever, sweating

If you currently have inflammation of the intestine or bowel (enteritis or colitis), this may temporarily get worse. If you currently have a blockage in your bowel, this can lead to Gastrografin staying in the bowel for longer than usual, which may damage the lining of the bowel.

Delayed reactions can occur, if you are concerned you should contact your doctor.

If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or the X-ray department staff/radiologist.

How to store Gastrografin

Keep out of the reach and sight of children.

Do not use Gastrografin after the expiry date which is stated on the label. The expiry date refers to the last day of that month.

Protect from light and X-rays. Do not store above 25°C.

Further Information What Gastrografin contains

The active substances are sodium amidotrizoate and meglumine amidotrizoate.

1ml of solution contains 100mg sodium amidotrizoate and 660mg meglumine amidotrizoate.

The other ingredients are disodium edetate, sodium hydroxide, saccharin sodium, anise oil, polysorbate 80, and purified water.

What Gastrografin looks like and contents of the pack

Each pack of Gastrografin contains ten 100ml brown glass bottles.

Marketing Authorisation Holder and Manufacturer

Marketing Authorisation Holder:

Bayer plc Bayer House Strawberry Hill Newbury Berkshire RG14 1JA UK

Manufacturer:

Bayer Schering Pharma AG Berlin Germany

or

BerliMed S.A Madrid Spain

This leaflet was last approved in: October 2008

Gastrografin is a registered trademark of Bayer Schering Pharma AG (formerly Schering AG).

To listen to or request a copy of this leaflet in Braille, large print or audio please call, free of charge:

0800 198 5000 (UK only)

Please be ready to give the following information:

Product name: Gastrografin Solution
Reference number: 00010/0537

This is a service provided by the Royal National Institute of the Blind.


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